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    Emid1 EMI domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 685462, updated on 27-Dec-2024

    Summary

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    Symbol
    Emid1provided by RGD
    Full Name
    EMI domain containing 1provided by RGD
    Primary source
    RGD:1593795
    See related
    EnsemblRapid:ENSRNOG00000033575 AllianceGenome:RGD:1593795
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1565846
    Summary
    Predicted to be an extracellular matrix structural constituent conferring tensile strength. Predicted to be involved in extracellular matrix organization. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and extracellular matrix. Predicted to be part of collagen type V trimer. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Orthologous to human EMID1 (EMI domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 56.3), Thymus (RPKM 49.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Emid1 in Genome Data Viewer
    Location:
    14q21
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 14 NC_086032.1 (84214530..84257628, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 14 NC_051349.1 (80000486..80043561, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 14 NC_005113.4 (85357221..85400396, complement)

    Chromosome 14 - NC_086032.1Genomic Context describing neighboring genes Neighboring gene EWS RNA-binding protein 1 Neighboring gene rhomboid domain containing 3 Neighboring gene kringle containing transmembrane protein 1 Neighboring gene chromosome 14 C22orf31 homolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Developmental expression and biochemical characterization of Emu family members. Leimeister C, et al. Dev Biol, 2002 Sep 15. PMID 12221002
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables extracellular matrix structural constituent conferring tensile strength IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in extracellular matrix organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of collagen trimer IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of collagen type V trimer IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in collagen-containing extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in extracellular matrix ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    EMI domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001401620.1 → NP_001388549.1  EMI domain-containing protein 1 isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000014
      UniProtKB/TrEMBL
      A0A8I5ZXK2
      Related
      ENSRNOP00000082254.1, ENSRNOT00000098869.2

    2. NM_001401621.1 → NP_001388550.1  EMI domain-containing protein 1 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000014
      UniProtKB/TrEMBL
      A0A8I6GER7
      Related
      ENSRNOP00000101401.1, ENSRNOT00000150844.1

    3. NM_001401622.1 → NP_001388551.1  EMI domain-containing protein 1 isoform 3 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000014
      UniProtKB/TrEMBL
      A0A8I6A757
      Related
      ENSRNOP00000087090.1, ENSRNOT00000105678.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086032.1 Reference GRCr8

      Range
      84214530..84257628 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008770369.4 → XP_008768591.1  EMI domain-containing protein 1 isoform X2

      Related
      ENSRNOP00000086266.2, ENSRNOT00000105384.2
      Conserved Domains (2) summary
      pfam01391
      Location:320 → 370
      Collagen; Collagen triple helix repeat (20 copies)
      pfam07546
      Location:35 → 100
      EMI; EMI domain

    2. XM_039092451.2 → XP_038948379.1  EMI domain-containing protein 1 isoform X1

      Related
      ENSRNOP00000054173.3, ENSRNOT00000057361.4
      Conserved Domains (2) summary
      pfam01391
      Location:321 → 370
      Collagen; Collagen triple helix repeat (20 copies)
      pfam07546
      Location:35 → 100
      EMI; EMI domain

    3. XM_039092452.2 → XP_038948380.1  EMI domain-containing protein 1 isoform X3

      Conserved Domains (1) summary
      pfam07546
      Location:35 → 100
      EMI; EMI domain

    RNA

    1. XR_005493011.2 RNA Sequence

    2. XR_005493012.2 RNA Sequence

    3. XR_005493010.2 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001109467.1: Suppressed sequence

      Description
      NM_001109467.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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