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    Pstk phosphoseryl-tRNA kinase [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361661, updated on 9-Dec-2024

    Summary

    Official Symbol
    Pstkprovided by RGD
    Official Full Name
    phosphoseryl-tRNA kinaseprovided by RGD
    Primary source
    RGD:1564300
    See related
    EnsemblRapid:ENSRNOG00000020605 AllianceGenome:RGD:1564300
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1564300
    Summary
    Predicted to enable L-seryl-tRNA(Sec) kinase activity and tRNA binding activity. Predicted to act upstream of or within selenocysteine incorporation. Orthologous to human PSTK (phosphoseryl-tRNA kinase). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 162.3), Muscle (RPKM 143.9) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Pstk in Genome Data Viewer
    Location:
    1q41
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (195587911..195598326)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (186157730..186168145)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (201950148..201960563)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene similar to human chromosome 10 open reading frame 88 Neighboring gene family with sequence similarity 24, member A Neighboring gene IKAROS family zinc finger 5 Neighboring gene acyl-CoA dehydrogenase, short/branched chain

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables L-seryl-tRNA(Sec) kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables tRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables tRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within selenocysteine incorporation ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    L-seryl-tRNA(Sec) kinase
    NP_001258158.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001271229.1NP_001258158.1  L-seryl-tRNA(Sec) kinase

      See identical proteins and their annotated locations for NP_001258158.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A6HWV9, A6HWW0, D3ZE35
      Related
      ENSRNOP00000027967.8, ENSRNOT00000027967.9
      Conserved Domains (1) summary
      TIGR03575
      Location:20358
      selen_PSTK_euk; L-seryl-tRNA(Sec) kinase, eukaryotic

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      195587911..195598326
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)