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    Wdr38 WD repeat domain 38 [ Mus musculus (house mouse) ]

    Gene ID: 76646, updated on 9-Dec-2024

    Summary

    Official Symbol
    Wdr38provided by MGI
    Official Full Name
    WD repeat domain 38provided by MGI
    Primary source
    MGI:MGI:1923896
    See related
    Ensembl:ENSMUSG00000035295 AllianceGenome:MGI:1923896
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700123D08Rik
    Summary
    Acts upstream of or within hematopoietic progenitor cell differentiation. Orthologous to human WDR38 (WD repeat domain 38). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in testis adult (RPKM 33.3) and ovary adult (RPKM 2.4) See more
    Orthologs
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    Genomic context

    See Wdr38 in Genome Data Viewer
    Location:
    2 B; 2 24.42 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (38888287..38891600)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (38998309..39001584)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 39801 Neighboring gene predicted gene, 29985 Neighboring gene STARR-positive B cell enhancer ABC_E5911 Neighboring gene STARR-positive B cell enhancer ABC_E4447 Neighboring gene ribosomal protein L35 Neighboring gene STARR-positive B cell enhancer mm9_chr2:38866813-38867114 Neighboring gene actin related protein 2/3 complex, subunit 5-like Neighboring gene golgin A1 Neighboring gene predicted gene, 26127

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General protein information

    Preferred Names
    WD repeat-containing protein 38
    Names
    novel WD domain, G-beta repeat domain containing protein (1700123D08Rik)

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029687.4NP_083963.1  WD repeat-containing protein 38

      See identical proteins and their annotated locations for NP_083963.1

      Status: VALIDATED

      Source sequence(s)
      AL844588
      Consensus CDS
      CCDS38119.1
      UniProtKB/Swiss-Prot
      Q9D994
      Related
      ENSMUSP00000108493.2, ENSMUST00000112872.2
      Conserved Domains (3) summary
      COG2319
      Location:18300
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:25300
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:3166
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      38888287..38891600
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036162672.1XP_036018565.1  WD repeat-containing protein 38 isoform X1

      Conserved Domains (2) summary
      cd00200
      Location:63294
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:66102
      7WD40; WD40 repeat [structural motif]
    2. XM_036162673.1XP_036018566.1  WD repeat-containing protein 38 isoform X2

      Conserved Domains (2) summary
      cd00200
      Location:25279
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:3166
      7WD40; WD40 repeat [structural motif]

    RNA

    1. XR_004940766.1 RNA Sequence