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    Gr22b Gustatory receptor 22b [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 117492, updated on 9-Dec-2024

    Summary

    Official Symbol
    Gr22bprovided by FlyBase
    Official Full Name
    Gustatory receptor 22bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0045500
    Locus tag
    Dmel_CG31931
    See related
    AllianceGenome:FB:FBgn0045500
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG31931; CR31931; Dmel\CG31931; GR22b; Gr22bP; Gr2940.4
    Summary
    Predicted to enable ligand-gated monoatomic ion channel activity and sweet taste receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of taste and monoatomic ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in several cellular components, including axon; dendrite; and neuronal cell body. Is expressed in several structures, including adult labellum sensillum; labellum; larval gnathal ganglion; larval pharyngeal gustatory receptor neurons; and organism subdivision. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Gr22b in Genome Data Viewer
    Location:
    22B2-22B2; 2-3 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (1792057..1793268, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (1792057..1793268, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Gustatory receptor 22d Neighboring gene Gustatory receptor 22c Neighboring gene Gustatory receptor 22a Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ligand-gated monoatomic ion channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables sweet taste receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables taste receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus involved in sensory perception of taste ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in monoatomic ion transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in sensory perception of taste IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in axon IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in dendrite IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    PubMed 
    is_active_in neuronal cell body IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    gustatory receptor 22b
    Names
    CG31931-PA
    Gr22b-PA
    gustatory receptor 2940.4
    NP_001014456.1
    • point mutation, may be evolving pseudogene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      1792057..1793268 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001014456.1NP_001014456.1  gustatory receptor 22b [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001014456.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P84180, Q59E12
      Conserved Domains (1) summary
      pfam08395
      Location:17385
      7tm_7; 7tm Chemosensory receptor