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    Tmem255b transmembrane protein 255B [ Mus musculus (house mouse) ]

    Gene ID: 272465, updated on 27-Nov-2024

    Summary

    Official Symbol
    Tmem255bprovided by MGI
    Official Full Name
    transmembrane protein 255Bprovided by MGI
    Primary source
    MGI:MGI:2685533
    See related
    Ensembl:ENSMUSG00000038457 AllianceGenome:MGI:2685533
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm687; Fam70b
    Summary
    Predicted to be located in membrane. Is expressed in utricle and vagus ganglion. Orthologous to human TMEM255B (transmembrane protein 255B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in ovary adult (RPKM 1.7), mammary gland adult (RPKM 1.2) and 19 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Tmem255b in Genome Data Viewer
    Location:
    8 A1.1; 8 6.0 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (13485118..13543434)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (13435113..13493434)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene ATPase, H+/K+ exchanging, beta polypeptide Neighboring gene G protein-coupled receptor kinase 1 Neighboring gene growth arrest specific 6 Neighboring gene predicted gene, 53399 Neighboring gene RIKEN cDNA 1700029H14 gene Neighboring gene STARR-seq mESC enhancer starr_20769 Neighboring gene RAS p21 protein activator 3 Neighboring gene predicted gene, 34795

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    General gene information

    Clone Names

    • FLJ20716

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    transmembrane protein 255B
    Names
    family with sequence similarity 70, member B
    protein FAM70B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001143671.1NP_001137143.1  transmembrane protein 255B isoform 1

      See identical proteins and their annotated locations for NP_001137143.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK131817, BC089620
      Consensus CDS
      CCDS52486.1
      UniProtKB/TrEMBL
      G3UWB7
      Related
      ENSMUSP00000130504.2, ENSMUST00000167505.3
      Conserved Domains (2) summary
      pfam13273
      Location:31104
      DUF4064; Protein of unknown function (DUF4064)
      pfam14967
      Location:16327
      FAM70; FAM70 protein
    2. NM_001143672.1NP_001137144.1  transmembrane protein 255B isoform 2

      See identical proteins and their annotated locations for NP_001137144.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region, compared to variant 1. The encoded protein (isoform 2) has a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AK131817, BC089620
      Consensus CDS
      CCDS52487.1
      UniProtKB/TrEMBL
      G5E908
      Related
      ENSMUSP00000127421.2, ENSMUST00000167071.9
      Conserved Domains (1) summary
      pfam14967
      Location:16306
      FAM70; FAM70 protein
    3. NM_001402814.1NP_001389743.1  transmembrane protein 255B isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC130818
    4. NM_001402815.1NP_001389744.1  transmembrane protein 255B isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC130818, AC134613
    5. NM_001402816.1NP_001389745.1  transmembrane protein 255B isoform 5 precursor

      Status: VALIDATED

      Source sequence(s)
      AC130818
    6. NM_001402817.1NP_001389746.1  transmembrane protein 255B isoform 6 precursor

      Status: VALIDATED

      Source sequence(s)
      AC130818, AC134613

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      13485118..13543434
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006508813.5XP_006508876.1  transmembrane protein 255B isoform X3

      Conserved Domains (1) summary
      pfam14967
      Location:1188
      FAM70; FAM70 protein
    2. XM_006508811.5XP_006508874.1  transmembrane protein 255B isoform X2

      Conserved Domains (1) summary
      pfam14967
      Location:16253
      FAM70; FAM70 protein
    3. XM_006508814.5XP_006508877.1  transmembrane protein 255B isoform X4

      Conserved Domains (1) summary
      pfam14967
      Location:16275
      FAM70; FAM70 protein

    RNA

    1. XR_004934836.1 RNA Sequence

    2. XR_003947295.2 RNA Sequence

    3. XR_004934837.1 RNA Sequence