U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Rnf207 ring finger protein 207 [ Mus musculus (house mouse) ]

    Gene ID: 433809, updated on 27-Nov-2024

    Summary

    Official Symbol
    Rnf207provided by MGI
    Official Full Name
    ring finger protein 207provided by MGI
    Primary source
    MGI:MGI:2684989
    See related
    Ensembl:ENSMUSG00000058498 AllianceGenome:MGI:2684989
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm143; D330010C22Rik
    Summary
    Predicted to enable Hsp70 protein binding activity and transmembrane transporter binding activity. Predicted to be involved in several processes, including positive regulation of voltage-gated potassium channel activity; regulation of cardiac muscle contraction; and regulation of heart looping. Predicted to be active in perinuclear region of cytoplasm. Orthologous to human RNF207 (ring finger protein 207). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in heart adult (RPKM 22.3), thymus adult (RPKM 12.6) and 8 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Rnf207 in Genome Data Viewer
    Location:
    4 E2; 4 83.02 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (152391475..152403686, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (152307018..152319076, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E6292 Neighboring gene STARR-seq mESC enhancer starr_12200 Neighboring gene acyl-CoA thioesterase 7 Neighboring gene STARR-positive B cell enhancer ABC_E9627 Neighboring gene STARR-positive B cell enhancer ABC_E4736 Neighboring gene G protein-coupled receptor 153 Neighboring gene STARR-positive B cell enhancer ABC_E3558 Neighboring gene hes family bHLH transcription factor 3 Neighboring gene RIKEN cDNA 9430083M05 gene Neighboring gene isoprenylcysteine carboxyl methyltransferase Neighboring gene STARR-positive B cell enhancer ABC_E846 Neighboring gene ribosomal protein L22 Neighboring gene chromodomain helicase DNA binding protein 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables Hsp70 protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables Hsp70 protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables Hsp70 protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-folding chaperone binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transmembrane transporter binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transmembrane transporter binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transmembrane transporter binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in perinuclear region of cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033489.2NP_001028661.2  RING finger protein 207

      See identical proteins and their annotated locations for NP_001028661.2

      Status: VALIDATED

      Source sequence(s)
      AK042379, AK052224, BQ553878
      Consensus CDS
      CCDS51393.1
      UniProtKB/Swiss-Prot
      A6PW94, Q3V3A7
      UniProtKB/TrEMBL
      B9EJ04
      Related
      ENSMUSP00000075540.6, ENSMUST00000076183.12
      Conserved Domains (3) summary
      smart00502
      Location:202321
      BBC; B-Box C-terminal domain
      cd16558
      Location:2264
      RING-HC_RNF207; RING finger, HC subclass, found in RING finger protein 207 (RNF207) and similar proteins
      cd19814
      Location:97150
      Bbox1_RNF207-like; B-box-type 1 zinc finger found in RING finger protein 207 (RNF207) and similar proteins

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      152391475..152403686 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006539010.5XP_006539073.1  RING finger protein 207 isoform X2

      UniProtKB/TrEMBL
      B9EJ04
      Conserved Domains (3) summary
      smart00502
      Location:202321
      BBC; B-Box C-terminal domain
      cd16558
      Location:2264
      RING-HC_RNF207; RING finger, HC subclass, found in RING finger protein 207 (RNF207) and similar proteins
      cd19814
      Location:97150
      Bbox1_RNF207-like; B-box-type 1 zinc finger found in RING finger protein 207 (RNF207) and similar proteins
    2. XM_011250295.4XP_011248597.1  RING finger protein 207 isoform X1

      UniProtKB/TrEMBL
      B9EJ04
      Conserved Domains (2) summary
      cd16558
      Location:2264
      RING-HC_RNF207; RING finger, HC subclass, found in RING finger protein 207 (RNF207) and similar proteins
      cd19814
      Location:97150
      Bbox1_RNF207-like; B-box-type 1 zinc finger found in RING finger protein 207 (RNF207) and similar proteins
    3. XM_011250296.2XP_011248598.1  RING finger protein 207 isoform X3

      UniProtKB/TrEMBL
      B9EJ04
      Conserved Domains (1) summary
      cd19814
      Location:548
      Bbox1_RNF207-like; B-box-type 1 zinc finger found in RING finger protein 207 (RNF207) and similar proteins
    4. XM_011250297.2XP_011248599.1  RING finger protein 207 isoform X4

    5. XM_030253643.1XP_030109503.1  RING finger protein 207 isoform X5

    6. XM_011250298.4XP_011248600.1  RING finger protein 207 isoform X5

    RNA

    1. XR_003954979.2 RNA Sequence