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    Psma5 proteasome subunit alpha 5 [ Mus musculus (house mouse) ]

    Gene ID: 26442, updated on 27-Nov-2024

    Summary

    Official Symbol
    Psma5provided by MGI
    Official Full Name
    proteasome subunit alpha 5provided by MGI
    Primary source
    MGI:MGI:1347009
    See related
    Ensembl:ENSMUSG00000068749 AllianceGenome:MGI:1347009
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ZETA
    Summary
    Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Part of proteasome core complex. Orthologous to human PSMA5 (proteasome 20S subunit alpha 5). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in liver E14 (RPKM 49.4), placenta adult (RPKM 48.3) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Psma5 in Genome Data Viewer
    Location:
    3 F3; 3 46.89 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (108164242..108187268)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (108256926..108279952)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene synaptophysin like 2 Neighboring gene SIVA1, apoptosis-inducing factor pseudogene Neighboring gene STARR-seq mESC enhancer starr_08682 Neighboring gene STARR-seq mESC enhancer starr_08684 Neighboring gene predicted gene, 19343 Neighboring gene sortilin 1 Neighboring gene myosin binding protein H-like Neighboring gene predicted gene 12522

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Chemically induced (ENU) (1)  1 citation
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC102091, MGC118067

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    is_active_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of proteasome complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of proteasome core complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of proteasome core complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of proteasome core complex, alpha-subunit complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of proteasome core complex, alpha-subunit complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of proteasome core complex, alpha-subunit complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    proteasome subunit alpha type-5
    Names
    alpha-5
    macropain zeta chain
    multicatalytic endopeptidase complex zeta chain
    proteasome (prosome, macropain) subunit, alpha type 5
    proteasome zeta chain
    NP_036097.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011967.3NP_036097.1  proteasome subunit alpha type-5

      See identical proteins and their annotated locations for NP_036097.1

      Status: PROVISIONAL

      Source sequence(s)
      AK143468
      Consensus CDS
      CCDS17755.1
      UniProtKB/Swiss-Prot
      Q9Z2U1
      UniProtKB/TrEMBL
      Q3TUI9, Q3TUX3, Q3UPK6
      Related
      ENSMUSP00000088057.6, ENSMUST00000090569.10
      Conserved Domains (1) summary
      cd03753
      Location:8220
      proteasome_alpha_type_5; The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      108164242..108187268
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)