U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Mark2 MAP/microtubule affinity regulating kinase 2 [ Mus musculus (house mouse) ]

    Gene ID: 13728, updated on 3-Dec-2024

    Summary

    Official Symbol
    Mark2provided by MGI
    Official Full Name
    MAP/microtubule affinity regulating kinase 2provided by MGI
    Primary source
    MGI:MGI:99638
    See related
    Ensembl:ENSMUSG00000024969 AllianceGenome:MGI:99638
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Emk; EMK-1; Par-1; Par-1b
    Summary
    Predicted to enable several functions, including ATP binding activity; magnesium ion binding activity; and protein kinase activity. Predicted to be involved in several processes, including generation of neurons; protein phosphorylation; and regulation of neuron projection development. Located in basal cortex and nucleus. Is active in glutamatergic synapse and postsynapse. Is expressed in brain; early conceptus; and oocyte. Orthologous to human MARK2 (microtubule affinity regulating kinase 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in duodenum adult (RPKM 24.0), colon adult (RPKM 22.0) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Mark2 in Genome Data Viewer
    Location:
    19 A; 19 5.32 cM
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (7252761..7319222, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (7275396..7341860, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 22113 Neighboring gene STARR-seq mESC enhancer starr_45459 Neighboring gene REST corepressor 2 Neighboring gene predicted gene 17227 Neighboring gene STARR-seq mESC enhancer starr_45463 Neighboring gene STARR-seq mESC enhancer starr_45464 Neighboring gene spindlin interactor and repressor of chromatin binding Neighboring gene STARR-seq mESC enhancer starr_45465 Neighboring gene RIKEN cDNA 1700105P06 gene Neighboring gene STARR-positive B cell enhancer ABC_E3240 Neighboring gene RAB11B, member RAS oncogene family, pseudogene 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • KIAA4207, mKIAA4207

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 3-phosphoinositide-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables AMP-activated protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ATP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables DNA-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables Rho-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables eukaryotic translation initiation factor 2alpha kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2AS1 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2AS121 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2AT120 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2AXS139 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2BS14 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2BS36 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3S10 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3S28 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3S57 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3T11 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3T3 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3T45 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3T6 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H4S1 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables magnesium ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables magnesium ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables molecular function activator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein serine/threonine kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein serine/threonine kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables ribosomal protein S6 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables tau protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables tau-protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables tau-protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables tau-protein kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in axon development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in establishment of cell polarity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in establishment of cell polarity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in establishment or maintenance of cell polarity regulating cell shape ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in establishment or maintenance of epithelial cell apical/basal polarity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in establishment or maintenance of epithelial cell apical/basal polarity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intracellular signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in intracellular signal transduction ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in neuron migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in neuron migration ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in peptidyl-serine phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of neuron projection development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of neuron projection development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein autophosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein phosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of axonogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of axonogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of cytoskeleton organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of microtubule cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of postsynapse organization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in actin filament ISO
    Inferred from Sequence Orthology
    more info
     
    located_in actin filament ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in basal cortex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    located_in dendrite ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lateral plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in microtubule bundle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in microtubule bundle ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in postsynapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    serine/threonine-protein kinase MARK2
    Names
    ELKL motif kinase 1
    PAR1 homolog b
    NP_001073857.1
    NP_001073858.1
    NP_001073859.1
    NP_001397177.1
    NP_001397178.1
    NP_001397179.1
    NP_031954.2
    XP_006526704.1
    XP_006526705.1
    XP_006526706.1
    XP_006526707.1
    XP_006526708.1
    XP_006526709.1
    XP_006526710.1
    XP_006526711.1
    XP_006526713.1
    XP_006526715.1
    XP_006526717.1
    XP_006526719.1
    XP_017173548.1
    XP_030106603.1
    XP_030106604.1
    XP_036017316.1
    XP_036017318.1
    XP_036017319.1
    XP_036017320.1
    XP_036017321.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080388.3NP_001073857.1  serine/threonine-protein kinase MARK2 isoform 2

      See identical proteins and their annotated locations for NP_001073857.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1.
      Source sequence(s)
      AC129188, AC140307
      Consensus CDS
      CCDS50378.1
      UniProtKB/TrEMBL
      A0A0R4J227, E9Q9N6
      Related
      ENSMUSP00000127827.2, ENSMUST00000164205.8
      Conserved Domains (4) summary
      cd12201
      Location:623721
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      smart00220
      Location:53304
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14406
      Location:322363
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:52304
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    2. NM_001080389.3NP_001073858.1  serine/threonine-protein kinase MARK2 isoform 3

      See identical proteins and their annotated locations for NP_001073858.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks one exon and contains an alternate exon in the 3' coding region, compared to variant 1. The encoded isoform (3) is shorter, compared to isoform 1.
      Source sequence(s)
      AC129188, AC140307
      Consensus CDS
      CCDS37903.1
      UniProtKB/TrEMBL
      A0A0R4J0B1, E9Q9N6
      Related
      ENSMUSP00000032557.9, ENSMUST00000032557.15
      Conserved Domains (4) summary
      cd12201
      Location:632730
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      smart00220
      Location:53304
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14406
      Location:322363
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:52304
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    3. NM_001080390.3NP_001073859.1  serine/threonine-protein kinase MARK2 isoform 4

      See identical proteins and their annotated locations for NP_001073859.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks part of the 5' coding region, uses an alternate 5'-terminal exon, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (4) has a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AC140307
      Consensus CDS
      CCDS37905.1
      UniProtKB/TrEMBL
      Q3T9A3, Q3U3A1
      Related
      ENSMUSP00000025921.9, ENSMUST00000025921.15
      Conserved Domains (3) summary
      cd12201
      Location:644742
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:289330
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:19271
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    4. NM_001410248.1NP_001397177.1  serine/threonine-protein kinase MARK2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC129188, AC140307
      UniProtKB/TrEMBL
      E9Q9N6
    5. NM_001410249.1NP_001397178.1  serine/threonine-protein kinase MARK2 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC129188, AC140307
      UniProtKB/Swiss-Prot
      Q05512, Q3T9L3, Q6PDR4, Q8BR95
      Related
      ENSMUSP00000129506.2, ENSMUST00000171721.8
    6. NM_001410250.1NP_001397179.1  serine/threonine-protein kinase MARK2 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC129188, AC140307
      UniProtKB/TrEMBL
      E9Q9N6
    7. NM_007928.4NP_031954.2  serine/threonine-protein kinase MARK2 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC129188, AC140307
      Consensus CDS
      CCDS37904.1
      UniProtKB/Swiss-Prot
      Q05512, Q3T9L3, Q6PDR4, Q8BR95
      UniProtKB/TrEMBL
      E9PWB5, E9QMP6
      Related
      ENSMUSP00000131684.2, ENSMUST00000165965.8
      Conserved Domains (4) summary
      cd12201
      Location:677775
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      smart00220
      Location:53304
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14406
      Location:322363
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:52304
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      7252761..7319222 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006526645.3XP_006526708.1  serine/threonine-protein kinase MARK2 isoform X4

      See identical proteins and their annotated locations for XP_006526708.1

      UniProtKB/TrEMBL
      Q3U3A1
      Conserved Domains (3) summary
      cd12201
      Location:709807
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:289330
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:19271
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    2. XM_036161427.1XP_036017320.1  serine/threonine-protein kinase MARK2 isoform X19

      UniProtKB/TrEMBL
      E9Q9N6
      Conserved Domains (3) summary
      cd12201
      Location:590688
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:289330
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:19271
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    3. XM_006526643.3XP_006526706.1  serine/threonine-protein kinase MARK2 isoform X3

      UniProtKB/Swiss-Prot
      Q05512, Q3T9L3, Q6PDR4, Q8BR95
      Conserved Domains (3) summary
      cd12201
      Location:742840
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:322363
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:52304
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    4. XM_036161428.1XP_036017321.1  serine/threonine-protein kinase MARK2 isoform X19

      UniProtKB/TrEMBL
      E9Q9N6
      Conserved Domains (3) summary
      cd12201
      Location:590688
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:289330
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:19271
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    5. XM_036161423.1XP_036017316.1  serine/threonine-protein kinase MARK2 isoform X7

      UniProtKB/TrEMBL
      E9Q9N6
      Conserved Domains (3) summary
      cd12201
      Location:689787
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:332373
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:62314
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    6. XM_006526647.3XP_006526710.1  serine/threonine-protein kinase MARK2 isoform X5

      UniProtKB/TrEMBL
      E9Q9N6
      Conserved Domains (3) summary
      cd12201
      Location:698796
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:332373
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:62314
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    7. XM_006526641.4XP_006526704.1  serine/threonine-protein kinase MARK2 isoform X1

      UniProtKB/TrEMBL
      F6ZS70
      Conserved Domains (3) summary
      cd12201
      Location:752850
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:332373
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:62314
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    8. XM_006526652.4XP_006526715.1  serine/threonine-protein kinase MARK2 isoform X14

      UniProtKB/TrEMBL
      E9Q9N6
      Conserved Domains (3) summary
      cd12201
      Location:642740
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:332373
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:62314
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    9. XM_006526650.4XP_006526713.1  serine/threonine-protein kinase MARK2 isoform X10

      UniProtKB/TrEMBL
      F6ZS70
      Conserved Domains (3) summary
      cd12201
      Location:681779
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:332373
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:62314
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    10. XM_006526648.4XP_006526711.1  serine/threonine-protein kinase MARK2 isoform X6

      UniProtKB/TrEMBL
      F6ZS70
      Conserved Domains (3) summary
      cd12201
      Location:696794
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:332373
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:62314
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    11. XM_006526644.5XP_006526707.1  serine/threonine-protein kinase MARK2 isoform X4

      See identical proteins and their annotated locations for XP_006526707.1

      UniProtKB/TrEMBL
      Q3U3A1
      Conserved Domains (3) summary
      cd12201
      Location:709807
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:289330
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:19271
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    12. XM_006526646.5XP_006526709.1  serine/threonine-protein kinase MARK2 isoform X4

      See identical proteins and their annotated locations for XP_006526709.1

      UniProtKB/TrEMBL
      Q3U3A1
      Conserved Domains (3) summary
      cd12201
      Location:709807
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:289330
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:19271
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    13. XM_017318059.3XP_017173548.1  serine/threonine-protein kinase MARK2 isoform X19

      UniProtKB/TrEMBL
      E9Q9N6
      Conserved Domains (3) summary
      cd12201
      Location:590688
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:289330
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:19271
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    14. XM_036161425.1XP_036017318.1  serine/threonine-protein kinase MARK2 isoform X13

      UniProtKB/TrEMBL
      Q3T9A3, Q3U3A1
      Conserved Domains (3) summary
      cd12201
      Location:644742
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:289330
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:19271
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    15. XM_036161426.1XP_036017319.1  serine/threonine-protein kinase MARK2 isoform X16

      UniProtKB/TrEMBL
      E9Q9N6
      Conserved Domains (3) summary
      cd12201
      Location:575673
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:289330
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:19271
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    16. XM_006526642.5XP_006526705.1  serine/threonine-protein kinase MARK2 isoform X2

      UniProtKB/TrEMBL
      F6ZS70
      Conserved Domains (3) summary
      cd12201
      Location:743841
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:332373
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:62314
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    17. XM_030250743.2XP_030106603.1  serine/threonine-protein kinase MARK2 isoform X12

      UniProtKB/Swiss-Prot
      Q05512, Q3T9L3, Q6PDR4, Q8BR95
      Conserved Domains (3) summary
      cd12201
      Location:662760
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:322363
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:52304
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    18. XM_030250744.2XP_030106604.1  serine/threonine-protein kinase MARK2 isoform X17

      UniProtKB/TrEMBL
      E9PYX3, E9Q9N6
      Related
      ENSMUSP00000126468.2, ENSMUST00000165286.8
      Conserved Domains (3) summary
      cd12201
      Location:617715
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:322363
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:52304
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    19. XM_006526654.5XP_006526717.1  serine/threonine-protein kinase MARK2 isoform X15

      UniProtKB/TrEMBL
      E9Q9N6
      Conserved Domains (3) summary
      cd12201
      Location:627725
      MARK2_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinase 2
      cd14406
      Location:332373
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:62314
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases
    20. XM_006526656.4XP_006526719.1  serine/threonine-protein kinase MARK2 isoform X18

      UniProtKB/TrEMBL
      F6ZS70
      Conserved Domains (2) summary
      cd14406
      Location:332373
      UBA_MARK2; UBA domain found in serine/threonine-protein kinase MARK2 and similar proteins
      cd14072
      Location:62314
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases