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    Fam162a family with sequence similarity 162, member A [ Mus musculus (house mouse) ]

    Gene ID: 70186, updated on 9-Dec-2024

    Summary

    Official Symbol
    Fam162aprovided by MGI
    Official Full Name
    family with sequence similarity 162, member Aprovided by MGI
    Primary source
    MGI:MGI:1917436
    See related
    Ensembl:ENSMUSG00000003955 AllianceGenome:MGI:1917436
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    HGTD-P; 2310056P07Rik
    Summary
    Involved in several processes, including cellular response to hypoxia; neuron apoptotic process; and positive regulation of release of cytochrome c from mitochondria. Located in mitochondrion. Is expressed in cerebral cortex subventricular zone and cerebral cortex ventricular layer. Orthologous to human FAM162A (family with sequence similarity 162 member A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in bladder adult (RPKM 58.3), limb E14.5 (RPKM 45.7) and 26 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Fam162a in Genome Data Viewer
    Location:
    16 B3; 16 25.43 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (35864214..35891931, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (36043844..36071561, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene karyopherin subunit alpha 1 Neighboring gene STARR-positive B cell enhancer ABC_E5540 Neighboring gene WD repeat domain 5B Neighboring gene STARR-seq mESC enhancer starr_40755 Neighboring gene mitochondrial matrix import factor 23 Neighboring gene STARR-seq mESC enhancer starr_40756 Neighboring gene STARR-seq mESC enhancer starr_40757 Neighboring gene predicted gene, 41450

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrial membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protein FAM162A
    Names
    E2-induced gene 5 protein homolog
    growth and transformation-dependent protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027342.2NP_081618.1  protein FAM162A

      See identical proteins and their annotated locations for NP_081618.1

      Status: VALIDATED

      Source sequence(s)
      CT573031
      Consensus CDS
      CCDS28146.1
      UniProtKB/Swiss-Prot
      Q9D6U8
      Related
      ENSMUSP00000004057.8, ENSMUST00000004057.9
      Conserved Domains (1) summary
      pfam06388
      Location:28153
      DUF1075; Protein of unknown function (DUF1075)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      35864214..35891931 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)