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    Zswim7 zinc finger SWIM-type containing 7 [ Mus musculus (house mouse) ]

    Gene ID: 69747, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zswim7provided by MGI
    Official Full Name
    zinc finger SWIM-type containing 7provided by MGI
    Primary source
    MGI:MGI:1916997
    See related
    Ensembl:ENSMUSG00000014243 AllianceGenome:MGI:1916997
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SWS1; 2410012H22Rik
    Summary
    Predicted to enable zinc ion binding activity. Predicted to be involved in double-strand break repair via homologous recombination and protein stabilization. Predicted to be located in nucleus. Predicted to be part of Shu complex. Human ortholog(s) of this gene implicated in 46 XX gonadal dysgenesis and spermatogenic failure 71. Orthologous to human ZSWIM7 (zinc finger SWIM-type containing 7). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 30.3), kidney adult (RPKM 11.1) and 27 other tissues See more
    Orthologs
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    Genomic context

    See Zswim7 in Genome Data Viewer
    Location:
    11 B2; 11 37.99 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (62158050..62172221, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (62267224..62281395, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene sperm antigen with calponin homology and coiled-coil domains 1 Neighboring gene predicted gene, 39985 Neighboring gene STARR-seq mESC enhancer starr_29695 Neighboring gene STARR-seq mESC enhancer starr_29696 Neighboring gene STARR-positive B cell enhancer ABC_E9139 Neighboring gene adenosine A2b receptor Neighboring gene tetratricopeptide repeat domain 19 Neighboring gene anaphase-promoting complex subunit 15 pseudogene Neighboring gene STARR-seq mESC enhancer starr_29697 Neighboring gene nuclear receptor co-repressor 1 Neighboring gene STARR-seq mESC enhancer starr_29699 Neighboring gene STARR-seq mESC enhancer starr_29702 Neighboring gene STARR-seq mESC enhancer starr_29703 Neighboring gene STARR-seq mESC enhancer starr_29704

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1)  1 citation
    • Targeted (1) 

    General gene information

    Markers

    Clone Names

    • MGC130274

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in double-strand break repair via homologous recombination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in double-strand break repair via homologous recombination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in double-strand break repair via homologous recombination ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein stabilization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein stabilization ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of Shu complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of Shu complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of Shu complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    zinc finger SWIM domain-containing protein 7
    Names
    SWIM domain-containing and Srs2-interacting protein 1 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027198.1NP_081474.1  zinc finger SWIM domain-containing protein 7

      See identical proteins and their annotated locations for NP_081474.1

      Status: VALIDATED

      Source sequence(s)
      AA027411, AK010472, BQ554850
      Consensus CDS
      CCDS48816.1
      UniProtKB/Swiss-Prot
      Q9CWQ2
      Related
      ENSMUSP00000072688.5, ENSMUST00000072916.5

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      62158050..62172221 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)