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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001122841.3 → NP_001116313.1 FERM domain-containing protein 1 isoform 2
See identical proteins and their annotated locations for NP_001116313.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. This variant encodes isoform 2 which has a shorter, distinct N-terminus, compared to isoform 1.
- Source sequence(s)
-
AK097579, AL133077, AL589733
- Consensus CDS
-
CCDS47518.1
- UniProtKB/TrEMBL
-
B7Z8G9
- Related
- ENSP00000414115.2, ENST00000440994.6
- Conserved Domains (4) summary
-
- smart00295
Location:3 → 196
- B41; Band 4.1 homologues
- pfam00373
Location:85 → 196
- FERM_M; FERM central domain
- pfam09379
Location:3 → 52
- FERM_N; FERM N-terminal domain
- cl17171
Location:189 → 274
- PH-like; Pleckstrin homology-like domain
-
NM_001394681.1 → NP_001381610.1 FERM domain-containing protein 1 isoform 3
Status: VALIDATED
- Source sequence(s)
-
AL589733
- Consensus CDS
-
CCDS94036.1
- UniProtKB/TrEMBL
- A0A2R8Y6M2, B7Z8G9
- Related
- ENSP00000495639.1, ENST00000336070.11
- Conserved Domains (3) summary
-
- cd13185
Location:169 → 277
- FERM_C_FRMD1_FRMD6; FERM domain C-lobe of FERM domain containing 1 and 6 proteins
- cd14473
Location:70 → 168
- FERM_B-lobe; FERM domain B-lobe
- cl28922
Location:11 → 62
- Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
-
NM_024919.6 → NP_079195.3 FERM domain-containing protein 1 isoform 1
See identical proteins and their annotated locations for NP_079195.3
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) encodes the longer isoform (1).
- Source sequence(s)
-
AL589733
- Consensus CDS
-
CCDS5306.1
- UniProtKB/Swiss-Prot
- B2RNV8, B3KUM6, Q5SZU7, Q8N878, Q9UFB0
- UniProtKB/TrEMBL
-
B7Z8G9
- Related
- ENSP00000283309.6, ENST00000283309.11
- Conserved Domains (4) summary
-
- smart00295
Location:56 → 264
- B41; Band 4.1 homologues
- pfam00373
Location:153 → 264
- FERM_M; FERM central domain
- pfam09379
Location:58 → 120
- FERM_N; FERM N-terminal domain
- cl17171
Location:257 → 342
- PH-like; Pleckstrin homology-like domain
RNA
-
NR_110312.2 RNA Sequence
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) uses an alternate 5' and 3' exon structure, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AK125963, AL133077, AL589733, DB019858