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narP DNA-binding transcriptional dual regulator NarP [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 949081, updated on 3-Dec-2024

Summary

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Official Symbol
narP
Official Full Name
DNA-binding transcriptional dual regulator NarP
Primary source
ECOCYC:EG11527
Locus tag
b2193
See related
ASAP:ABE-0007259
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2185
Summary
The protein belongs to the LuxR/UhpA family. [More information is available at EcoCyc: EG11527].
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Genomic context

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Sequence:
NC_000913.3 (2290500..2291147)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene tRNA-Pro Neighboring gene pseudo Neighboring gene IS5 family transposase and trans-activator Neighboring gene holocytochrome c synthase CcmH component Neighboring gene thiol:disulfide oxidoreductase CcmG Neighboring gene holocytochrome c synthase CcmF component Neighboring gene periplasmic heme chaperone

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Differential regulation by the homologous response regulators NarL and NarP of Escherichia coli K-12 depends on DNA binding site arrangement. Darwin AJ, et al. Mol Microbiol, 1997 Aug. PMID 9302020
  2. A Gibbs sampler for identification of symmetrically structured, spaced DNA motifs with improved estimation of the signal length. Favorov AV, et al. Bioinformatics, 2005 May 15. PMID 15728117
  3. Functional roles for the GerE-family carboxyl-terminal domains of nitrate response regulators NarL and NarP of Escherichia coli K-12. Lin AV, et al. Microbiology (Reading), 2010 Oct. PMID 20634237, Free PMC Article
  4. Nitrate regulation of anaerobic respiratory gene expression in Escherichia coli. Stewart V. Mol Microbiol, 1993 Aug. PMID 8412692
  5. Synthesis of the NarP response regulator of nitrate respiration in Escherichia coli is regulated at multiple levels by Hfq and small RNAs. Brosse A, et al. Nucleic Acids Res, 2022 Jul 8. PMID 35748881, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Synthesis of the NarP response regulator of nitrate respiration in Escherichia coli is regulated at multiple levels by Hfq and small RNAs.
    Title: Synthesis of the NarP response regulator of nitrate respiration in Escherichia coli is regulated at multiple levels by Hfq and small RNAs.
  2. NarL and NarP carboxyl-terminal domains activate transcription from Nar class II control regions.
    Title: Functional roles for the GerE-family carboxyl-terminal domains of nitrate response regulators NarL and NarP of Escherichia coli K-12.
  3. Analysis of the DNA sequence of the ydhY promoter region (PydhY) revealed the presence of four heptameric sequences similar to NarL/P binding sites
    Title: Characterization of the Escherichia coli K-12 ydhYVWXUT operon: regulation by FNR, NarL and NarP.
  4. analysis of FNR regulon and its interactions with nitrate, nitrite, NarXL, and NarQP
    Title: A reassessment of the FNR regulon and transcriptomic analysis of the effects of nitrate, nitrite, NarXL, and NarQP as Escherichia coli K12 adapts from aerobic to anaerobic growth.
  5. binding of NarL/NarP appears to insulate the nrf promoter from the effects of integration host factor
    Title: The Escherichia coli K-12 NarL and NarP proteins insulate the nrf promoter from the effects of integration host factor.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA binding IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in nitrate assimilation IEA
Inferred from Electronic Annotation
more info
  
involved_in phosphorelay signal transduction system IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
DNA-binding transcriptional dual regulator NarP

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2290500..2291147
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416697.1 DNA-binding transcriptional dual regulator NarP [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416697.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376WXJ7, A0A5B9AZT7
    Conserved Domains (1) summary
    PRK10403
    Location:1 → 215
    PRK10403; nitrate/nitrite response regulator protein NarP
Nucleotide Protein
Heading Accession and Version

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