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nfi endonuclease V [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948502, updated on 3-Dec-2024

Summary

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Official Symbol
nfi
Official Full Name
endonuclease V
Primary source
ECOCYC:EG11915
Locus tag
b3998
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3990; yjaF
Summary
nfi encodes endonuclease V (EndoV) of Escherichia coli. [More information is available at EcoCyc: EG11915].
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Genomic context

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Sequence:
NC_000913.3 (4198790..4199461)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene RNA decapping hydrolase Neighboring gene uroporphyrinogen decarboxylase Neighboring gene DUF416 domain-containing protein YjaG Neighboring gene DNA-binding protein HU-alpha

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Endonuclease V protects Escherichia coli against specific mutations caused by nitrous acid. Schouten KA, et al. Mutat Res, 1999 Dec 7. PMID 10606815
  2. Endonuclease V of Escherichia coli. Gates FT 3rd, et al. J Biol Chem, 1977 Mar 10. PMID 14159
  3. On the recognition and cleavage mechanism of Escherichia coli endodeoxyribonuclease V, a possible DNA repair enzyme. Demple B, et al. J Biol Chem, 1982 Mar 25. PMID 6277916
  4. Strand-specific cleavage of mismatch-containing DNA by deoxyinosine 3'-endonuclease from Escherichia coli. Yao M, et al. J Biol Chem, 1994 Dec 16. PMID 7989304
  5. Purification and characterization of a novel deoxyinosine-specific enzyme, deoxyinosine 3' endonuclease, from Escherichia coli. Yao M, et al. J Biol Chem, 1994 Jun 10. PMID 8206931

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on complete protein
    Title: nfi, the gene for endonuclease V in Escherichia coli K-12.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables RNA endonuclease activity, producing 5'-phosphomonoesters IBA
Inferred from Biological aspect of Ancestor
more info
  
enables deoxyribonuclease V activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables deoxyribonuclease V activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables deoxyribonuclease V activity IEA
Inferred from Electronic Annotation
more info
  
enables endonuclease activity IEA
Inferred from Electronic Annotation
more info
  
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables single-stranded RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA repair IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within DNA repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IC
Inferred by Curator
more info
 PubMed 

General protein information

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Preferred Names
endonuclease V

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4198790..4199461
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418426.2 endonuclease V [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418426.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2X1NTY5
    Conserved Domains (1) summary
    PRK11617
    Location:1 → 223
    PRK11617; deoxyribonuclease V
Nucleotide Protein
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