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rffC RffC [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948298, updated on 17-Dec-2024

Summary

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Official Symbol
rffC
Official Full Name
RffC
Primary source
ECOCYC:EG11455
Locus tag
b3790
See related
ASAP:ABE-0012382
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3782; rff; wecD; yifH
Summary
GNAT acetyltransferase family. [More information is available at EcoGene: EG11455]. dTDP-fucosamine acetyltransferase catalyzes the synthesis of TDP-4-acetamido-4,6-dideoxy-D-galactose, which is utilized in the biosynthesis of Enterobacterial Common Antigen (ECA). [More information is available at EcoCyc: EG11455].
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Genomic context

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Sequence:
NC_000913.3 (3974467..3975141)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene UDP-N-acetylglucosamine 2-epimerase Neighboring gene UDP-N-acetyl-D-mannosamine dehydrogenase Neighboring gene dTDP-glucose 4,6-dehydratase 2 Neighboring gene glucose-1-phosphate thymidylyltransferase 2 Neighboring gene dTDP-4-dehydro-6-deoxy-D-glucose transaminase Neighboring gene lipid IIIECA flippase Neighboring gene TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crystal structure of TDP-fucosamine acetyltransferase (WecD) from Escherichia coli, an enzyme required for enterobacterial common antigen synthesis. Hung MN, et al. J Bacteriol, 2006 Aug. PMID 16855251, Free PMC Article
  2. THYMIDINE DIPHOSPHATE 4-ACETAMIDO-4, 6-DIDEOXYHEXOSES. I. ENZYMATIC SYNTHESIS BY STRAINS OF ESCHERICHIA COLI. MATSUHASHI M, et al. J Biol Chem, 1964 Aug. PMID 14235522
  3. Physical map location of the rffC and rffA genes of Escherichia coli. Barr K, et al. J Bacteriol, 1993 Sep. PMID 8366065, Free PMC Article
  4. Genetic location of genes encoding enterobacterial common antigen. Meier U, et al. J Bacteriol, 1985 Aug. PMID 3894334, Free PMC Article
  5. Nucleotide sequence of the Escherichia coli rfe gene involved in the synthesis of enterobacterial common antigen. Molecular cloning of the rfe-rff gene cluster. Meier-Dieter U, et al. J Biol Chem, 1992 Jan 15. PMID 1730666

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

General protein information

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Preferred Names
RffC
YP_026256.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3974467..3975141
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_026256.2 RffC [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for YP_026256.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6D0F2B7
    Conserved Domains (1) summary
    PRK10975
    Location:38 → 224
    PRK10975; dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase
Nucleotide Protein
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