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uhpB sensory histidine kinase UhpB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948195, updated on 17-Dec-2024

Summary

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Official Symbol
uhpB
Official Full Name
sensory histidine kinase UhpB
Primary source
ECOCYC:EG11052
Locus tag
b3668
See related
ASAP:ABE-0011993
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3659
Summary
Probable false positive lipoprotein prediction, Cys not conserved, 10 CM TMs predicted. [More information is available at EcoGene: EG11052]. UhpB belongs to the phosphorelay system UhpB-UhpC-UhpA and is involved in the regulation of the uptake of hexose phosphates . [More information is available at EcoCyc: EG11052].
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Genomic context

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Sequence:
NC_000913.3 (3848634..3850136, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene hexose-6-phosphate:phosphate antiporter Neighboring gene inner membrane protein sensing glucose-6-phosphate Neighboring gene DNA-binding transcriptional activator UhpA Neighboring gene acetohydroxy acid synthase I subunit IlvN Neighboring gene acetohydroxy acid synthase I subunit IlvB

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The phosphoryl transfer domain of UhpB interacts with the response regulator UhpA. Wright JS 3rd, et al. J Bacteriol, 2001 May. PMID 11325944, Free PMC Article
  2. Promoter elements required for positive control of transcription of the Escherichia coli uhpT gene. Merkel TJ, et al. J Bacteriol, 1992 May. PMID 1569008, Free PMC Article
  3. Role of uhp genes in expression of the Escherichia coli sugar-phosphate transport system. Weston LA, et al. J Bacteriol, 1988 Aug. PMID 3042748, Free PMC Article
  4. Action of receiver and activator modules of UhpA in transcriptional control of the Escherichia coli sugar phosphate transport system. Webber CA, et al. Mol Microbiol, 1995 Mar. PMID 7596290
  5. The family of organo-phosphate transport proteins includes a transmembrane regulatory protein. Kadner RJ, et al. J Bioenerg Biomembr, 1993 Dec. PMID 8144492

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphoprotein phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphorelay sensor kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphorelay sensor kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables phosphorelay sensor kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in phosphorelay signal transduction system IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within signal transduction IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within signal transduction IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
sensory histidine kinase UhpB
NP_418124.4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3848634..3850136 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418124.4 sensory histidine kinase UhpB [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418124.4

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A1X3JAQ9, A0A376FUW3
    Conserved Domains (1) summary
    PRK11644
    Location:4 → 498
    PRK11644; signal transduction histidine-protein kinase/phosphatase UhpB
Nucleotide Protein
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