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mtlD mannitol-1-phosphate 5-dehydrogenase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948117, updated on 3-Dec-2024

Summary

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Official Symbol
mtlD
Official Full Name
mannitol-1-phosphate 5-dehydrogenase
Primary source
ECOCYC:EG10616
Locus tag
b3600
See related
ASAP:ABE-0011767
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3589
Summary
The protein has been purified as both a monomer and an apparent dimer. [More information is available at EcoCyc: EG10616].
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Genomic context

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Sequence:
NC_000913.3 (3774424..3775572)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF3302 domain-containing protein YibI Neighboring gene mannitol-specific PTS enzyme IICBA component Neighboring gene transcriptional repressor MtlR Neighboring gene protein YibT Neighboring gene DUF2810 domain-containing protein YibL

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Rapid turnover of mannitol-1-phosphate in Escherichia coli. Rosenberg H, et al. J Bacteriol, 1984 Apr. PMID 6425270, Free PMC Article
  2. Enzymatic properties, renaturation and metabolic role of mannitol-1-phosphate dehydrogenase from Escherichia coli. Teschner W, et al. Biochimie, 1990 Jan. PMID 2111176
  3. Purification and properties of D-mannitol-1-phosphate dehydrogenase and D-glucitol-6-phosphate dehydrogenase from Escherichia coli. Novotny MJ, et al. J Bacteriol, 1984 Sep. PMID 6384188, Free PMC Article
  4. Mutations affecting the dissimilation of mannitol by Escherichia coli K-12. Solomon E, et al. J Bacteriol, 1972 Aug. PMID 4559737, Free PMC Article
  5. Nucleotide sequence of the mannitol (mtl) operon in Escherichia coli. Davis T, et al. Mol Microbiol, 1988 May. PMID 3135464

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on complete protein
    Title: Purification and properties of D-mannitol-1-phosphate dehydrogenase and D-glucitol-6-phosphate dehydrogenase from Escherichia coli.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables mannitol-1-phosphate 5-dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mannitol-1-phosphate 5-dehydrogenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables mannitol-1-phosphate 5-dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mannitol catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within mannitol catabolic process IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within mannitol catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mannitol metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
mannitol-1-phosphate 5-dehydrogenase
NP_418057.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3774424..3775572
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418057.1 mannitol-1-phosphate 5-dehydrogenase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418057.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0S2I9Z3, B1A9U1, Q0PWM5
    Conserved Domains (1) summary
    PRK02318
    Location:1 → 382
    PRK02318; mannitol-1-phosphate 5-dehydrogenase; Provisional
Nucleotide Protein
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Gene LinkOut

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