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dctR putative DNA-binding transcriptional regulator DctR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948021, updated on 3-Dec-2024

Summary

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Official Symbol
dctR
Official Full Name
putative DNA-binding transcriptional regulator DctR
Primary source
ECOCYC:EG11889
Locus tag
b3507
See related
ASAP:ABE-0011454
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3491; yhiF
Summary
DctR is in the EvgAS regulon. [More information is available at EcoGene: EG11889]. DctR is a predicted transcriptional regulator whose target may be dctA. [More information is available at EcoCyc: EG11889].
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Genomic context

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Sequence:
NC_000913.3 (3654683..3655213)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene IS5 family transposase and trans-activator Neighboring gene starvation lipoprotein Neighboring gene inner membrane protein YhiD Neighboring gene periplasmic acid stress chaperone HdeB

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. DctR contributes to the virulence of avian pathogenic Escherichia coli through regulation of type III secretion system 2 expression. Zhang Y, et al. Vet Res, 2021 Jul 6. PMID 34229767, Free PMC Article
  2. Increased adherence to Caco-2 cells caused by disruption of the yhiE and yhiF genes in enterohemorrhagic Escherichia coli O157:H7. Tatsuno I, et al. Infect Immun, 2003 May. PMID 12704134, Free PMC Article
  3. GadE (YhiE): a novel activator involved in the response to acid environment in Escherichia coli. Hommais F, et al. Microbiology (Reading), 2004 Jan. PMID 14702398
  4. atp Mutants of Escherichia coli fail to grow on succinate due to a transport deficiency. Boogerd FC, et al. J Bacteriol, 1998 Nov. PMID 9811641, Free PMC Article
  5. Products of the Escherichia coli acid fitness island attenuate metabolite stress at extremely low pH and mediate a cell density-dependent acid resistance. Mates AK, et al. J Bacteriol, 2007 Apr. PMID 17259322, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. DctR contributes to the virulence of avian pathogenic Escherichia coli through regulation of type III secretion system 2 expression.
    Title: DctR contributes to the virulence of avian pathogenic Escherichia coli through regulation of type III secretion system 2 expression.
  2. RcsB forms heterodimers with MatA (also known as EcpR) and with DctR
    Title: Interaction of the RcsB Response Regulator with Auxiliary Transcription Regulators in Escherichia coli.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cellular stress response to acidic pH IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putative DNA-binding transcriptional regulator DctR

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3654683..3655213
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417964.1 putative DNA-binding transcriptional regulator DctR [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417964.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7KD89
    Conserved Domains (2) summary
    smart00421
    Location:113 → 169
    HTH_LUXR; helix_turn_helix, Lux Regulon
    COG2197
    Location:2 → 168
    CitB; DNA-binding response regulator, NarL/FixJ family, contains REC and HTH domains [Signal transduction mechanisms, Transcription]
Nucleotide Protein
Heading Accession and Version

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