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rlmJ 23S rRNA m(6)A2030 methyltransferase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948012, updated on 17-Dec-2024

Summary

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Official Symbol
rlmJ
Official Full Name
23S rRNA m(6)A2030 methyltransferase
Primary source
ECOCYC:EG12234
Locus tag
b3499
See related
ASAP:ABE-0011428
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3484; yhiR
Summary
yhiR is a homologue of the H. influenzae competence gene comJ. [More information is available at EcoCyc: EG12234].
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Genomic context

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Sequence:
NC_000913.3 (3645385..3646227)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene 16S rRNA m(2)G1516 methyltransferase Neighboring gene oligopeptidase A Neighboring gene glutathione reductase (NADPH) Neighboring gene membrane toxin DinQ

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transforming DNA uptake gene orthologs do not mediate spontaneous plasmid transformation in Escherichia coli. Sun D, et al. J Bacteriol, 2009 Feb. PMID 19011021, Free PMC Article
  2. DNA as a nutrient: novel role for bacterial competence gene homologs. Finkel SE, et al. J Bacteriol, 2001 Nov. PMID 11591672, Free PMC Article
  3. The last rRNA methyltransferase of E. coli revealed: the yhiR gene encodes adenine-N6 methyltransferase specific for modification of A2030 of 23S ribosomal RNA. Golovina AY, et al. RNA, 2012 Sep. PMID 22847818, Free PMC Article
  4. Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes. Sofia HJ, et al. Nucleic Acids Res, 1994 Jul 11. PMID 8041620, Free PMC Article
  5. Escherichia coli competence gene homologs are essential for competitive fitness and the use of DNA as a nutrient. Palchevskiy V, et al. J Bacteriol, 2006 Jun. PMID 16707682, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 23S rRNA (adenine(2030)-N(6))-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 23S rRNA (adenine(2030)-N(6))-methyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables 23S rRNA (adenine(2030)-N(6))-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables rRNA (adenine-N6-)-methyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables rRNA methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within carbon utilization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in methylation IEA
Inferred from Electronic Annotation
more info
  
involved_in rRNA base methylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in rRNA base methylation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in rRNA base methylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within rRNA base methylation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
23S rRNA m(6)A2030 methyltransferase
NP_417956.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3645385..3646227
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417956.1 23S rRNA m(6)A2030 methyltransferase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417956.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5B9AMX9, A0A8S0FGP4
    Conserved Domains (1) summary
    COG2961
    Location:2 → 280
    RlmJ; 23S rRNA A2030 N6-methylase RlmJ [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
Heading Accession and Version

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