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zntR DNA-binding transcriptional activator ZntR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947786, updated on 3-Dec-2024

Summary

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Official Symbol
zntR
Official Full Name
DNA-binding transcriptional activator ZntR
Primary source
ECOCYC:EG11969
Locus tag
b3292
See related
ASAP:ABE-0010793
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3279; yhdM
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Genomic context

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Sequence:
NC_000913.3 (3438705..3439130, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene NAD-binding component of Trk potassium transporters Neighboring gene large conductance mechanosensitive channel Neighboring gene alternative ribosome-rescue factor A Neighboring gene DUF1992 domain-containing protein YhdN Neighboring gene 50S ribosomal subunit protein L17

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Ligand-controlled proteolysis of the Escherichia coli transcriptional regulator ZntR. Pruteanu M, et al. J Bacteriol, 2007 Apr. PMID 17220226, Free PMC Article
  2. The functional analysis of directed amino-acid alterations in ZntR from Escherichia coli. Khan S, et al. Biochem Biophys Res Commun, 2002 Dec 6. PMID 12445820
  3. ZntR-mediated transcription of zntA responds to nanomolar intracellular free zinc. Wang D, et al. J Inorg Biochem, 2012 Jun. PMID 22459916, Free PMC Article
  4. Simulating in vitro transcriptional response of zinc homeostasis system in Escherichia coli. Cui J, et al. BMC Syst Biol, 2008 Oct 24. PMID 18950480, Free PMC Article
  5. DNA distortion mechanism for transcriptional activation by ZntR, a Zn(II)-responsive MerR homologue in Escherichia coli. Outten CE, et al. J Biol Chem, 1999 Dec 31. PMID 10608803

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription activator activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables cis-regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables zinc ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within positive regulation of DNA-templated transcription ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DNA-binding transcriptional activator ZntR

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3438705..3439130 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417751.1 DNA-binding transcriptional activator ZntR [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417751.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A377BX35
    Conserved Domains (1) summary
    PRK09514
    Location:1 → 140
    zntR; Zn(2+)-responsive transcriptional regulator
Nucleotide Protein
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