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yhaK bicupin-related protein [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947620, updated on 3-Dec-2024

Summary

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Official Symbol
yhaK
Official Full Name
bicupin-related protein
Primary source
ECOCYC:G7620
Locus tag
b3106
See related
ASAP:ABE-0010217
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3097
Summary
Yhak is a low abudance protein. yhhW and yhaK are paralogs, and homologs of human Pirin nuclear protein. [More information is available at EcoGene: EG12750]. YhaK belongs to a subclass of the bicupin family and may be involved in chloride binding or sensing of oxidative stress . [More information is available at EcoCyc: G7620].
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Genomic context

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Sequence:
NC_000913.3 (3254319..3255020)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative inner membrane protein Neighboring gene DNA-binding transcriptional activator YhaJ Neighboring gene uncharacterized protein YhaL Neighboring gene putative L-cysteine desulfidase CyuA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome-wide transposon mutagenesis identifies a role for host neuroendocrine stress hormones in regulating the expression of virulence genes in Salmonella. Spencer H, et al. J Bacteriol, 2010 Feb. PMID 19933366, Free PMC Article
  2. The crystal structure of the protein YhaK from Escherichia coli reveals a new subclass of redox sensitive enterobacterial bicupins. Gurmu D, et al. Proteins, 2009 Jan. PMID 18561187
  3. Prominent roles of the NorR and Fur regulators in the Escherichia coli transcriptional response to reactive nitrogen species. Mukhopadhyay P, et al. Proc Natl Acad Sci U S A, 2004 Jan 20. PMID 14718666, Free PMC Article
  4. Thermofluor-based high-throughput stability optimization of proteins for structural studies. Ericsson UB, et al. Anal Biochem, 2006 Oct 15. PMID 16962548
  5. Global gene expression profiling of asymptomatic bacteriuria Escherichia coli during biofilm growth in human urine. Hancock V, et al. Infect Immun, 2007 Feb. PMID 17145952, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
bicupin-related protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3254319..3255020
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417577.1 bicupin-related protein [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417577.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5D8MVT3
    Conserved Domains (1) summary
    COG1741
    Location:1 → 233
    YhaK; Redox-sensitive bicupin YhaK, pirin superfamily [General function prediction only]
Nucleotide Protein
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