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queE putative 7-carboxy-7-deazaguanine synthase QueE [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947527, updated on 17-Dec-2024

Summary

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Official Symbol
queE
Official Full Name
putative 7-carboxy-7-deazaguanine synthase QueE
Primary source
ECOCYC:G7443
Locus tag
b2777
See related
ASAP:ABE-0009101
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2771; ygcF
Summary
B. subtilis homolog is involved in queuosine preQ0 synthesis (Reader, 2004). [More information is available at EcoGene: EG13034].
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Genomic context

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Sequence:
NC_000913.3 (2904747..2905418, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative transport protein YqcE Neighboring gene putative sugar kinase YgcE Neighboring gene cell envelope stress response protein YqcG Neighboring gene TPM domain-containing protein YgcG

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Antimicrobial peptides trigger a division block in Escherichia coli through stimulation of a signalling system. Yadavalli SS, et al. Nat Commun, 2016 Jul 29. PMID 27471053, Free PMC Article
  2. Radical SAM enzyme QueE defines a new minimal core fold and metal-dependent mechanism. Dowling DP, et al. Nat Chem Biol, 2014 Feb. PMID 24362703, Free PMC Article
  3. Crystal structure of AdoMet radical enzyme 7-carboxy-7-deazaguanine synthase from Escherichia coli suggests how modifications near [4Fe-4S] cluster engender flavodoxin specificity. Grell TAJ, et al. Protein Sci, 2019 Jan. PMID 30341796, Free PMC Article
  4. The phosphotransferase system-dependent sucrose utilization regulon in enteropathogenic Escherichia coli strains is located in a variable chromosomal region containing iap sequences. Treviño-Quintanilla LG, et al. J Mol Microbiol Biotechnol, 2007. PMID 17693719
  5. Biosynthesis of the 7-deazaguanosine hypermodified nucleosides of transfer RNA. Iwata-Reuyl D. Bioorg Chem, 2003 Feb. PMID 12697167

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Crystal structure of AdoMet radical enzyme 7-carboxy-7-deazaguanine synthase from Escherichia coli suggests how modifications near [4Fe-4S] cluster engender flavodoxin specificity.
    Title: Crystal structure of AdoMet radical enzyme 7-carboxy-7-deazaguanine synthase from Escherichia coli suggests how modifications near [4Fe-4S] cluster engender flavodoxin specificity.
  2. QueE - a type of SAM enzyme
    Title: Radical SAM enzyme QueE defines a new minimal core fold and metal-dependent mechanism.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables S-adenosyl-L-methionine binding IEA
Inferred from Electronic Annotation
more info
  
enables carbon-nitrogen lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of cytokinesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in queuosine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within queuosine biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cell division site IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
putative 7-carboxy-7-deazaguanine synthase QueE
NP_417257.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2904747..2905418 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417257.1 putative 7-carboxy-7-deazaguanine synthase QueE [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417257.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0AAN5FUQ9
    Conserved Domains (1) summary
    TIGR04322
    Location:9 → 223
    rSAM_QueE_Ecoli; putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE
Nucleotide Protein
Heading Accession and Version

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