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gcvR putative transcriptional regulator GcvR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946950, updated on 3-Dec-2024

Summary

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Official Symbol
gcvR
Official Full Name
putative transcriptional regulator GcvR
Primary source
ECOCYC:EG11149
Locus tag
b2479
See related
ASAP:ABE-0008168
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2475; yffD
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Genomic context

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Sequence:
NC_000913.3 (2599906..2600478)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene outer membrane protein assembly factor BamC Neighboring gene 4-hydroxy-tetrahydrodipicolinate synthase Neighboring gene thiol peroxidase Neighboring gene hydrogenase 4 component A Neighboring gene hydrogenase 4 component B

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Promoter characterization and constitutive expression of the Escherichia coli gcvR gene. Ghrist AC, et al. J Bacteriol, 1998 Apr. PMID 9537378, Free PMC Article
  2. GcvR interacts with GcvA to inhibit activation of the Escherichia coli glycine cleavage operon. Ghrist AC, et al. Microbiology (Reading), 2001 Aug. PMID 11495998
  3. A molecular analysis of the 53.3 minute region of the Escherichia coli linkage map. Andrews SC, et al. J Gen Microbiol, 1991 Feb. PMID 2016588
  4. Characterization of the Escherichia coli gcvR gene encoding a negative regulator of gcv expression. Ghrist AC, et al. J Bacteriol, 1995 Sep. PMID 7665475, Free PMC Article
  5. Glycine binds the transcriptional accessory protein GcvR to disrupt a GcvA/GcvR interaction and allow GcvA-mediated activation of the Escherichia coli gcvTHP operon. Heil G, et al. Microbiology (Reading), 2002 Jul. PMID 12101307

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on mature peptide
    Title: Promoter characterization and constitutive expression of the Escherichia coli gcvR gene.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Process Evidence Code Pubs
involved_in DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
putative transcriptional regulator GcvR

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2599906..2600478
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416974.4 putative transcriptional regulator GcvR [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416974.4

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6C9GB60
    Conserved Domains (1) summary
    PRK11589
    Location:1 → 190
    gcvR; glycine cleavage system transcriptional repressor; Provisional
Nucleotide Protein
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