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gatD galactitol-1-phosphate 5-dehydrogenase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946598, updated on 17-Dec-2024

Summary

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Official Symbol
gatD
Official Full Name
galactitol-1-phosphate 5-dehydrogenase
Primary source
ECOCYC:EG12417
Locus tag
b2091
See related
ASAP:ABE-0006924
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2084
Summary
Some strains of Escherichia coli K-12 are able to utilize galactitol as the sole source of carbon. [More information is available at EcoCyc: EG12417].
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Genomic context

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Sequence:
NC_000913.3 (2171833..2172873, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene lipid kinase YegS Neighboring gene pseudo Neighboring gene IS3 element protein InsE Neighboring gene IS3 element protein InsF Neighboring gene pseudo Neighboring gene galactitol-specific PTS enzyme IIB component

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The crystal structure of galactitol-1-phosphate 5-dehydrogenase from Escherichia coli K12 provides insights into its anomalous behavior on IMAC processes. Esteban-Torres M, et al. FEBS Lett, 2012 Sep 21. PMID 22979983
  2. Enantioselective oxidation of galactitol 1-phosphate by galactitol-1-phosphate 5-dehydrogenase from Escherichia coli. Benavente R, et al. Acta Crystallogr D Biol Crystallogr, 2015 Jul. PMID 26143925
  3. Genotypic exclusion: a novel relationship between the ribitol-arabitol and galactitol genes of E. coli. Link CD, et al. Mol Gen Genet, 1983. PMID 6343795
  4. Mapping of mglB, the structural gene of the galactose-binding protein of Escherichia coli. Boos W, et al. Mol Gen Genet, 1981. PMID 6278261
  5. Mapping of the gene for cytidine deaminase (cdd) in Escherichia coli K-12. Josephsen J, et al. J Bacteriol, 1983 Apr. PMID 6339482, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables galactitol-1-phosphate 5-dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables galactitol-1-phosphate 5-dehydrogenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables galactitol-1-phosphate 5-dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
  
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables zinc ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within galactitol catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in galactitol metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
galactitol-1-phosphate 5-dehydrogenase
NP_416594.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2171833..2172873 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416594.1 galactitol-1-phosphate 5-dehydrogenase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416594.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8T5YFA5
    Conserved Domains (1) summary
    PRK10309
    Location:1 → 344
    PRK10309; galactitol-1-phosphate 5-dehydrogenase
Nucleotide Protein
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