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ynfL putative DNA-binding transcriptional regulator YnfL [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946136, updated on 3-Dec-2024

Summary

Official Symbol
ynfL
Official Full Name
putative DNA-binding transcriptional regulator YnfL
Primary source
ECOCYC:G6853
Locus tag
b1595
See related
ASAP:ABE-0005326
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1590
Summary
A ynfLM clone conferred hypersensitivity to acriflavin, but a ynfM-alone expression clone did not, leading the authors to conclude that overexpression of the putative regulator YnfL was responsible for the Acr-S phenoptype. [More information is available at EcoGene: EG13850].
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Genomic context

Sequence:
NC_000913.3 (1668699..1669592, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative chloride:H(+) antiporter ClcB Neighboring gene dethiobiotin synthetase BidA Neighboring gene DNA-binding transcriptional repressor Mlc Neighboring gene putative transporter YnfM Neighboring gene periplasmic chaperone Asr

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of protein-DNA complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
putative DNA-binding transcriptional regulator YnfL

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1668699..1669592 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416112.1 putative DNA-binding transcriptional regulator YnfL [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416112.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6M9WVL8
    Conserved Domains (2) summary
    cd08414
    Location:94289
    PBP2_LTTR_aromatics_like; The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold
    pfam00126
    Location:564
    HTH_1; Bacterial regulatory helix-turn-helix protein, lysR family