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rluB 23S rRNA pseudouridine(2605) synthase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945840, updated on 3-Dec-2024

Summary

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Official Symbol
rluB
Official Full Name
23S rRNA pseudouridine(2605) synthase
Primary source
ECOCYC:EG12433
Locus tag
b1269
See related
ASAP:ABE-0004259
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1263; yciL
Summary
Ribosome-associated protein (Jiang, 2007). [More information is available at EcoGene: EG12433]. RluB is the pseudouridine synthase that catalyzes formation of pseudouridine at position 2605 in 23S rRNA. [More information is available at EcoCyc: EG12433].
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Genomic context

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Sequence:
NC_000913.3 (1326852..1327727)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene RNase AM Neighboring gene putative RNA-binding protein YciO Neighboring gene DUF2207 domain-containing protein YciQ Neighboring gene cobinamide/cobalamin adenosyltransferase Neighboring gene putative oxidoreductase Neighboring gene S49 peptidase family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Altered cobalamin metabolism in Escherichia coli btuR mutants affects btuB gene regulation. Lundrigan MD, et al. J Bacteriol, 1989 Jan. PMID 2644187, Free PMC Article
  2. An indigenous posttranscriptional modification in the ribosomal peptidyl transferase center confers resistance to an array of protein synthesis inhibitors. Toh SM, et al. J Mol Biol, 2008 Jul 18. PMID 18554609, Free PMC Article
  3. Four newly located pseudouridylate residues in Escherichia coli 23S ribosomal RNA are all at the peptidyltransferase center: analysis by the application of a new sequencing technique. Bakin A, et al. Biochemistry, 1993 Sep 21. PMID 8373778
  4. Phenotypic screening of Escherichia coli K-12 Tn5 insertion libraries, using whole-genome oligonucleotide microarrays. Winterberg KM, et al. Appl Environ Microbiol, 2005 Jan. PMID 15640221, Free PMC Article
  5. Intrinsic and extrinsic approaches for detecting genes in a bacterial genome. Borodovsky M, et al. Nucleic Acids Res, 1994 Nov 11. PMID 7984428, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 23S rRNA pseudouridine(2605) synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables pseudouridine synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables rRNA pseudouridine synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables rRNA pseudouridine synthase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in enzyme-directed rRNA pseudouridine synthesis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within enzyme-directed rRNA pseudouridine synthesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in pseudouridine synthesis IEA
Inferred from Electronic Annotation
more info
  
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
23S rRNA pseudouridine(2605) synthase
NP_415785.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1326852..1327727
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415785.1 23S rRNA pseudouridine(2605) synthase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415785.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A7D7PU83
    Conserved Domains (1) summary
    PRK10700
    Location:1 → 289
    PRK10700; 23S rRNA pseudouridine(2605) synthase RluB
Nucleotide Protein
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