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sapF putrescine ABC exporter ATP binding protein SapF [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945335, updated on 3-Dec-2024

Summary

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Official Symbol
sapF
Official Full Name
putrescine ABC exporter ATP binding protein SapF
Primary source
ECOCYC:EG12305
Locus tag
b1290
See related
ASAP:ABE-0004339
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1285
Summary
Characterized initially in Salmonella. [More information is available at EcoGene: EG12305]. SapABCDF (Sensitive to antimicrobial peptides) is a member of the ATP Binding Cassette (ABC) transporter superfamily . [More information is available at EcoCyc: EG12305].
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Genomic context

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Sequence:
NC_000913.3 (1351828..1352634, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene enoyl-[acyl-carrier-protein] reductase Neighboring gene DUF559 domain-containing protein YcjD Neighboring gene putrescine ABC exporter ATP binding protein SapD Neighboring gene putrescine ABC exporter membrane protein SapC Neighboring gene putrescine ABC exporter membrane subunit SapB Neighboring gene putative periplasmic binding protein SapA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Salmonella protein that is required for resistance to antimicrobial peptides and transport of potassium. Parra-Lopez C, et al. EMBO J, 1994 Sep 1. PMID 8076592, Free PMC Article
  2. Resistance to host antimicrobial peptides is necessary for Salmonella virulence. Groisman EA, et al. Proc Natl Acad Sci U S A, 1992 Dec 15. PMID 1465423, Free PMC Article
  3. Identification of the ABC protein SapD as the subunit that confers ATP dependence to the K+-uptake systems Trk(H) and Trk(G) from Escherichia coli K-12. Harms C, et al. Microbiology (Reading), 2001 Nov. PMID 11700350
  4. Requirement of a large K+-uptake capacity and of extracytoplasmic protease activity for protamine resistance of Escherichia coli. Stumpe S, et al. Arch Microbiol, 1997 Feb-Mar. PMID 9133319
  5. ATP-binding cassette transporters in Escherichia coli. Moussatova A, et al. Biochim Biophys Acta, 2008 Sep. PMID 18634750

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding ISM
Inferred from Sequence Model
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables putrescine transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in peptide transport NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within putrescine transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
Non-traceable Author Statement
more info
 PubMed 
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putrescine ABC exporter ATP binding protein SapF

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1351828..1352634 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415806.1 putrescine ABC exporter ATP binding protein SapF [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415806.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376DHY0
    Conserved Domains (1) summary
    PRK15112
    Location:2 → 268
    PRK15112; peptide ABC transporter ATP-binding protein SapF
Nucleotide Protein
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