U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

thrL thr operon leader peptide [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 944742, updated on 3-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
thrL
Official Full Name
thr operon leader peptide
Primary source
ECOCYC:EG11277
Locus tag
b0001
See related
ASAP:ABE-0000006
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0001
Summary
The ThrL leader peptide controls by attenuation the expression of the thrLABC operon, which encodes four out of the five enzymes of threonine biosynthesis pathway, in response to the threonine and isoleucine levels . [More information is available at EcoCyc: EG11277].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000913.3 (190..255)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene fused aspartate kinase/homoserine dehydrogenase 1 Neighboring gene homoserine kinase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Attenuation regulation in the thr operon of Escherichia coli K-12: molecular cloning and transcription of the controlling region. Lynn SP, et al. J Bacteriol, 1982 Oct. PMID 6811557, Free PMC Article
  2. DNA sequence change of a deletion mutation abolishing attenuation control of the threonine operon of E. coli K12. Parsot C, et al. Mol Gen Genet, 1982. PMID 6298575
  3. Initiation, pausing, and termination of transcription in the threonine operon regulatory region of Escherichia coli. Gardner JF. J Biol Chem, 1982 Apr 10. PMID 6277952
  4. Isolation and footprint analysis of the Escherichia coli thr leader paused transcription complex. Yang MT, et al. Nucleic Acids Res, 1991 Apr 11. PMID 1709279, Free PMC Article
  5. Regulation of the threonine operon: tandem threonine and isoleucine codons in the control region and translational control of transcription termination. Gardner JF. Proc Natl Acad Sci U S A, 1979 Apr. PMID 287010, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Gene Ontology Provided by EcoCyc

Process Evidence Code Pubs
involved_in threonine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within transcriptional attenuation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transcriptional attenuation by ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
thr operon leader peptide

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    190..255
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414542.1 thr operon leader peptide [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414542.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0AD86
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.