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lpxO lipid A hydroxylase LpxO [ Burkholderia mallei ]

Gene ID: 92976738, updated on 3-Dec-2024

Summary

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Gene symbol
lpxO
Gene description
lipid A hydroxylase LpxO
Locus tag
atcc23344_RS04825
Gene type
protein coding
Organism
Burkholderia mallei (strain: ATCC 23344, nat-host: Homo sapiens, type-material: type strain of Burkholderia mallei)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Betaproteobacteria; Burkholderiales; Burkholderiaceae; Burkholderia; pseudomallei group
Old locus tag
atcc23344_000940
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Genomic context

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Location:
chromosome: 2

2 - NZ_CP124607.1Genomic Context describing neighboring genes Neighboring gene D-erythronate dehydrogenase Neighboring gene aspartyl/asparaginyl beta-hydroxylase domain-containing protein Neighboring gene choline ABC transporter substrate-binding protein Neighboring gene GlxA family transcriptional regulator

Genomic regions, transcripts, and products

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Genomic Sequence:
NZ_CP124607.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Deciphering tissue-induced Klebsiella pneumoniae lipid A structure. Llobet E, et al. Proc Natl Acad Sci U S A, 2015 Nov 17. PMID 26578797, Free PMC Article
  2. The role of Pseudomonas lipopolysaccharide in cystic fibrosis airway infection. Moskowitz SM, et al. Subcell Biochem, 2010. PMID 20593270, Free PMC Article
  3. Role of pagL and lpxO in Bordetella bronchiseptica lipid A biosynthesis. MacArthur I, et al. J Bacteriol, 2011 Sep. PMID 21764941, Free PMC Article
  4. Oxygen requirement for the biosynthesis of the S-2-hydroxymyristate moiety in Salmonella typhimurium lipid A. Function of LpxO, A new Fe2+/alpha-ketoglutarate-dependent dioxygenase homologue. Gibbons HS, et al. J Biol Chem, 2000 Oct 20. PMID 10903325
  5. An inner membrane dioxygenase that generates the 2-hydroxymyristate moiety of Salmonella lipid A. Gibbons HS, et al. Biochemistry, 2008 Mar 4. PMID 18254598, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
lipid A hydroxylase LpxO

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NZ_CP124607.1 Reference assembly

    Range
    1139427..1140326 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_004194983.1 MULTISPECIES: lipid A hydroxylase LpxO [Burkholderia]

    See identical proteins and their annotated locations for WP_004194983.1

    UniProtKB/TrEMBL
    A0A0H2WCR6, A0A0H3I090, A0AAX0UBF5, A2RYE3, A3P6K2, Q3JLE8, Q63KD8
Nucleotide Protein
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