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kstR cholesterol catabolism transcriptional regulator KstR [ Gordonia polyisoprenivorans VH2 ]

Gene ID: 90161161, updated on 14-May-2024

Summary

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Gene symbol
kstR
Gene description
cholesterol catabolism transcriptional regulator KstR
Locus tag
GPOL_RS20855
Gene type
protein coding
Organism
Gordonia polyisoprenivorans VH2 (strain: VH2, culture-collection: DSM:44266)
Lineage
Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae; Gordonia
Old locus tag
GPOL_c41550
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Genomic context

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Sequence:
NC_016906.1 (4728546..4729190)

NC_016906.1Genomic Context describing neighboring genes Neighboring gene acyl-CoA dehydrogenase family protein Neighboring gene acyl-CoA dehydrogenase family protein Neighboring gene acyl-CoA dehydrogenase Neighboring gene DUF1059 domain-containing protein Neighboring gene alpha/beta hydrolase family protein Neighboring gene phenylacetaldehyde dehydrogenase StyD

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_016906.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Deciphering the transcriptional regulation of cholesterol catabolic pathway in mycobacteria: identification of the inducer of KstR repressor. García-Fernández E, et al. J Biol Chem, 2014 Jun 20. PMID 24802756, Free PMC Article
  2. A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. Kendall SL, et al. Mol Microbiol, 2007 Aug. PMID 17635188, Free PMC Article
  3. The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis. Ho NA, et al. J Biol Chem, 2016 Apr 1. PMID 26858250, Free PMC Article
  4. Cholesterol utilization in mycobacteria is controlled by two TetR-type transcriptional regulators: kstR and kstR2. Kendall SL, et al. Microbiology (Reading), 2010 May. PMID 20167624, Free PMC Article
  5. Involvement of two latex-clearing proteins during rubber degradation and insights into the subsequent degradation pathway revealed by the genome sequence of Gordonia polyisoprenivorans strain VH2. Hiessl S, et al. Appl Environ Microbiol, 2012 Apr. PMID 22327575, Free PMC Article

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
cholesterol catabolism transcriptional regulator KstR

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_016906.1 Reference assembly

    Range
    4728546..4729190
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_014361414.1 cholesterol catabolism transcriptional regulator KstR [Gordonia polyisoprenivorans]

    See identical proteins and their annotated locations for WP_014361414.1

    UniProtKB/TrEMBL
    H6MTT0
Nucleotide Protein
Heading Accession and Version