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mazF2 toxin MazF2 [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 888134, updated on 6-Oct-2023

Summary

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Gene symbol
mazF2
Gene description
toxin MazF2
Locus tag
Rv0659c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
Also known as
mt4
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Genomic context

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Sequence:
NC_000962.3 (754685..754993, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene antitoxin VapB6 Neighboring gene integral membrane protein Neighboring gene antitoxin MazE2 Neighboring gene ribonuclease VapC7 Neighboring gene antitoxin VapB7 Neighboring gene arylsulfatase AtsD

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  2. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
  3. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
toxin MazF2
NP_215173.1
  • part of toxin-antitoxin (TA) operon with Rv0660c. This region is a possible MT-complex-specific genomic island (See Becq et al., 2007 PMID:17545187).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    754685..754993 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_215173.1 toxin MazF2 [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_215173.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4LST1
    Conserved Domains (1) summary
    COG2337
    Location:1 → 102
    MazF; mRNA-degrading endonuclease, toxin component of the MazEF toxin-antitoxin module [Defense mechanisms]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WII1.1

Gene LinkOut

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Molecular Biology Databases
Research Materials