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sigH ECF RNA polymerase sigma factor SigH [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 888094, updated on 6-Oct-2023

Summary

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Gene symbol
sigH
Gene description
ECF RNA polymerase sigma factor SigH
Locus tag
Rv3223c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
Also known as
rpoE
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Genomic context

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Sequence:
NC_000962.3 (3598901..3599551, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene acetyl-CoA carboxylase biotin carboxyl carrier protein subunit Neighboring gene anti-sigma factor RshA Neighboring gene hypothetical protein Neighboring gene iron-regulated short-chain dehydrogenase/reductase Neighboring gene GCN5-like N-acetyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural basis for transcription initiation by bacterial ECF σ factors. Li L, et al. Nat Commun, 2019 Mar 11. PMID 30858373, Free PMC Article
  2. Functional genomics reveals extended roles of the Mycobacterium tuberculosis stress response factor sigmaH. Mehra S, et al. J Bacteriol, 2009 Jun. PMID 19376862, Free PMC Article
  3. Critical role of a single position in the -35 element for promoter recognition by Mycobacterium tuberculosis SigE and SigH. Song T, et al. J Bacteriol, 2008 Mar. PMID 18192397, Free PMC Article
  4. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
  5. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Study reports the crystal structure of an ECF sigma factor-RNAP holoenzyme comprising M. tuberculosis RNAP and sigH at 2.70 A resolution.
    Title: Structural basis for transcription initiation by bacterial ECF σ factors.
  2. SigH caused the induction of the ATP-dependent clp proteolysis regulon.
    Title: Functional genomics reveals extended roles of the Mycobacterium tuberculosis stress response factor sigmaH.
  3. Data determined that SigH recognize nearly identical promoters as sigB, with differences at the 3' end of the -35 element distinguishing between SigE- and SigH-dependent promoters.
    Title: Critical role of a single position in the -35 element for promoter recognition by Mycobacterium tuberculosis SigE and SigH.
Submit: New GeneRIF Correction

General gene information

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Homology

General protein information

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Preferred Names
ECF RNA polymerase sigma factor SigH
NP_217739.1
  • belongs to the sigma-70 factor family, ECF subfamily

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    3598901..3599551 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_217739.1 ECF RNA polymerase sigma factor SigH [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_217739.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    R4M6M3
    Conserved Domains (1) summary
    TIGR02947
    Location:18 → 209
    SigH_actino; RNA polymerase sigma-70 factor, TIGR02947 family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WGH9.1

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