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kdpD sensor protein KdpD [ Mycobacterium tuberculosis H37Rv ]

Gene ID: 886084, updated on 9-Aug-2024

Summary

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Gene symbol
kdpD
Gene description
sensor protein KdpD
Locus tag
Rv1028c
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
Lineage
Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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Genomic context

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Sequence:
NC_000962.3 (1149104..1151686, complement)

NC_000962.3Genomic Context describing neighboring genes Neighboring gene membrane protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene transcriptional regulator KdpE Neighboring gene membrane protein KdpF Neighboring gene potassium-transporting ATPase subunit A Neighboring gene potassium-transporting ATPase subunit B

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000962.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. RegX3-dependent transcriptional activation of kdpDE and repression of rv0500A are linked to potassium homeostasis in Mycobacterium tuberculosis. Bagchi S, et al. FEBS J, 2024 May. PMID 38414198
  2. Rv1027c-Rv1028c encode functional KdpDE two--component system in Mycobacterium tuberculosis. Agrawal R, et al. Biochem Biophys Res Commun, 2014 Apr 18. PMID 24667597
  3. FRET reveals multiple interaction states between two component signalling system proteins of M. tuberculosis. Agrawal R, et al. Biochim Biophys Acta, 2016 Jul. PMID 27102281
  4. Interaction of the sensor module of Mycobacterium tuberculosis H37Rv KdpD with members of the Lpr family. Steyn AJ, et al. Mol Microbiol, 2003 Feb. PMID 12581360
  5. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. RegX3-dependent transcriptional activation of kdpDE and repression of rv0500A are linked to potassium homeostasis in Mycobacterium tuberculosis.
    Title: RegX3-dependent transcriptional activation of kdpDE and repression of rv0500A are linked to potassium homeostasis in Mycobacterium tuberculosis.
  2. KdpDE/NarSL interact with each other in unphosphorylated state and phosphorylation affects the interaction, which is reflected as reduction in FRET ratio.
    Title: FRET reveals multiple interaction states between two component signalling system proteins of M. tuberculosis.
  3. Identified are His(642) and Asp(52) as conserved phosphorylation sites in KdpD and KdpE respectively and by Surface plasmon resonance analysis confirmed the physical interaction between them.
    Title: Rv1027c-Rv1028c encode functional KdpDE two--component system in Mycobacterium tuberculosis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

General protein information

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Preferred Names
sensor protein KdpD
NP_215544.1
  • Belongs to universal stress protein family.

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000962.3 Reference assembly

    Range
    1149104..1151686 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_215544.1 sensor protein KdpD [Mycobacterium tuberculosis H37Rv]

    See identical proteins and their annotated locations for NP_215544.1

    Status: PROVISIONAL

    Conserved Domains (1) summary
    COG2205
    Location:7 → 860
    KdpD; K+-sensing histidine kinase KdpD [Signal transduction mechanisms]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P9WGL3.1

Gene LinkOut

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