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gltR two-component response regulator GltR [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 882907, updated on 18-Sep-2024

Summary

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Gene symbol
gltR
Gene description
two-component response regulator GltR
Locus tag
PA3192
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Genomic context

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Sequence:
NC_002516.2 (3583616..3584344, complement)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene sugar ABC transporter substrate-binding protein Neighboring gene two-component sensor Neighboring gene glucokinase Neighboring gene phosphogluconate dehydratase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A two-component response regulator, gltR, is required for glucose transport activity in Pseudomonas aeruginosa PAO1. Sage AE, et al. J Bacteriol, 1996 Oct. PMID 8830708, Free PMC Article
  2. GtrS and GltR form a two-component system: the central role of 2-ketogluconate in the expression of exotoxin A and glucose catabolic enzymes in Pseudomonas aeruginosa. Daddaoua A, et al. Nucleic Acids Res, 2014 Jul. PMID 24920832, Free PMC Article
  3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
  5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. GtrS and GltR form a two-component system that regulates the expression from the promoters Pedd/gap-1, PoprB and Pglk, which control the expression of genes involved in glucose metabolism and transport.
    Title: GtrS and GltR form a two-component system: the central role of 2-ketogluconate in the expression of exotoxin A and glucose catabolic enzymes in Pseudomonas aeruginosa.
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General gene information

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Homology

Gene Ontology Provided by PseudoCAP

Function Evidence Code Pubs
enables phosphorelay response regulator activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of D-glucose transmembrane transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
two-component response regulator GltR
NP_251882.1
  • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    3583616..3584344 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_251882.1 two-component response regulator GltR [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_251882.1

    Status: PROVISIONAL

    Conserved Domains (1) summary
    COG0745
    Location:8 → 234
    OmpR; DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain [Signal transduction mechanisms, Transcription]
Nucleotide Protein
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