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INPP4B inositol polyphosphate-4-phosphatase type II B [ Homo sapiens (human) ]

Gene ID: 8821, updated on 27-Nov-2024

Summary

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Official Symbol
INPP4Bprovided by HGNC
Official Full Name
inositol polyphosphate-4-phosphatase type II Bprovided by HGNC
Primary source
HGNC:HGNC:6075
See related
Ensembl:ENSG00000109452 MIM:607494; AllianceGenome:HGNC:6075
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
INPP4B encodes the inositol polyphosphate 4-phosphatase type II, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate. There is limited data to suggest that the human type II enzyme is subject to alternative splicing, as has been established for the type I enzyme. [provided by RefSeq, Jul 2008]
Expression
Ubiquitous expression in lymph node (RPKM 4.4), urinary bladder (RPKM 4.1) and 24 other tissues See more
Orthologs
mouse all
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Genomic context

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See INPP4B in Genome Data Viewer
Location:
4q31.21
Exon count:
50
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (142023160..142846535, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (145340544..146163746, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (142944313..143767688, complement)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr4:142501441-142502640 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:142546083-142546797 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21938 Neighboring gene long intergenic non-protein coding RNA 2276 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:142628696-142629196 Neighboring gene interleukin 15 Neighboring gene MPRA-validated peak5125 silencer Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:142803658-142804281 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:142804282-142804904 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:142823512-142824114 Neighboring gene ribosomal protein L5 pseudogene 13 Neighboring gene LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated pseudogene 4 Neighboring gene uncharacterized LOC101927613 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21939 Neighboring gene uncharacterized LOC105377457 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:143768211-143768797 Neighboring gene uncharacterized LOC124900788 Neighboring gene USP38 divergent transcript Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21940 Neighboring gene LysM domain containing 4 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. A tumor suppressor function for the lipid phosphatase INPP4B in melanocytic neoplasms. Perez-Lorenzo R, et al. J Invest Dermatol, 2014 May. PMID 24288008
  2. INPP4B restrains cell proliferation and metastasis via regulation of the PI3K/AKT/SGK pathway. Chen Y, et al. J Cell Mol Med, 2018 May. PMID 29516642, Free PMC Article
  3. Identification of inositol polyphosphate 4-phosphatase type II as a novel tumor resistance biomarker in human laryngeal cancer HEp-2 cells. Kim JS, et al. Cancer Biol Ther, 2012 Nov. PMID 22895072, Free PMC Article
  4. Down-regulation of Inositol Polyphosphate 4-Phosphatase Type II Expression in Colorectal Carcinoma. Sung JY, et al. Anticancer Res, 2017 Oct. PMID 28982866
  5. INPP4B overexpression suppresses migration, invasion and angiogenesis of human prostate cancer cells. Chen H, et al. Clin Exp Pharmacol Physiol, 2017 Jun. PMID 28261855

See all (80) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. [Preliminary Study of the Role of INPP4B in Promoting Colorectal Cancer Metastasis and the Mechanisms Involved].
    Title: [Preliminary Study of the Role of INPP4B in Promoting Colorectal Cancer Metastasis and the Mechanisms Involved].
  2. Role of INPP4B in the proliferation, migration, invasion, and survival of human endometrial cancer cells.
    Title: Role of INPP4B in the proliferation, migration, invasion, and survival of human endometrial cancer cells.
  3. INPP4B promotes PDAC aggressiveness via PIKfyve and TRPML-1-mediated lysosomal exocytosis.
    Title: INPP4B promotes PDAC aggressiveness via PIKfyve and TRPML-1-mediated lysosomal exocytosis.
  4. Investigating the multifaceted cooperation of autophagy, PI3K/AKT signaling pathways, and INPP4B gene in de novo acute myeloid leukemia patients.
    Title: Investigating the multifaceted cooperation of autophagy, PI3K/AKT signaling pathways, and INPP4B gene in de novo acute myeloid leukemia patients.
  5. Regulation of B-1 cell numbers and B cell-mediated antibody production by Inpp4b.
    Title: Regulation of B-1 cell numbers and B cell-mediated antibody production by Inpp4b.
  6. The INPP4B paradox: Like PTEN, but different.
    Title: The INPP4B paradox: Like PTEN, but different.
  7. INPP4B promotes PI3Kalpha-dependent late endosome formation and Wnt/beta-catenin signaling in breast cancer.
    Title: INPP4B promotes PI3Kα-dependent late endosome formation and Wnt/β-catenin signaling in breast cancer.
  8. Exosomes derived from human bone marrow mesenchymal stem cells transfer miR-222-3p to suppress acute myeloid leukemia cell proliferation by targeting IRF2/INPP4B.
    Title: Exosomes derived from human bone marrow mesenchymal stem cells transfer miR-222-3p to suppress acute myeloid leukemia cell proliferation by targeting IRF2/INPP4B.
  9. IRF2-INPP4B axis inhibits apoptosis of acute myeloid leukaemia cells via regulating T helper 1/2 cell differentiation.
    Title: IRF2-INPP4B axis inhibits apoptosis of acute myeloid leukaemia cells via regulating T helper 1/2 cell differentiation.
  10. Expression and functional characterization of INPP4B in gallbladder cancer patients and gallbladder cancer cells.
    Title: Expression and functional characterization of INPP4B in gallbladder cancer patients and gallbladder cancer cells.
Submit: New GeneRIF Correction See all GeneRIFs (64)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC132014

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables inositol-1,3,4-trisphosphate 4-phosphatase activity TAS
Traceable Author Statement
more info
  
enables inositol-3,4-bisphosphate 4-phosphatase activity TAS
Traceable Author Statement
more info
  
enables phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity TAS
Traceable Author Statement
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in inositol phosphate metabolic process TAS
Traceable Author Statement
more info
  
involved_in phosphatidylinositol biosynthetic process TAS
Traceable Author Statement
more info
  
involved_in phosphatidylinositol dephosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in signal transduction TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol TAS
Traceable Author Statement
more info
  

General protein information

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Preferred Names
inositol polyphosphate 4-phosphatase type II
Names
inositol polyphosphate 4-phosphatase II; 4-phosphatase II
inositol polyphosphate-4-phosphatase, type II, 105kDa
type II inositol 3,4-bisphosphate 4-phosphatase
NP_001095139.1
NP_001317969.1
NP_001372263.1
NP_001372264.1
NP_001372265.1
NP_001372266.1
NP_001372267.1
NP_001372268.1
NP_001372269.1
NP_001372270.1
NP_001372271.1
NP_001372272.1
NP_001372273.1
NP_001372276.1
NP_001372277.1
NP_001372279.1
NP_001372280.1
NP_001372286.1
NP_001372291.1
NP_001372308.1
NP_001372309.1
NP_001372310.1
NP_001372311.1
NP_001372312.1
NP_001372379.1
NP_001372381.1
NP_001372383.1
NP_001372384.1
NP_001372386.1
NP_001372387.1
NP_001372388.1
NP_001372389.1
NP_001372390.1
NP_003857.2
XP_011530693.1
XP_016864286.1
XP_016864287.1
XP_024310041.1
XP_024310042.1
XP_047272308.1
XP_047272309.1
XP_047272310.1
XP_047272312.1
XP_047272313.1
XP_047272314.1
XP_047272315.1
XP_047272316.1
XP_047272317.1
XP_047272318.1
XP_047272319.1
XP_047272321.1
XP_047272322.1
XP_047272323.1
XP_047272324.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001101669.3 → NP_001095139.1  inositol polyphosphate 4-phosphatase type II isoform 1

    See identical proteins and their annotated locations for NP_001095139.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (1).
    Source sequence(s)
    AC108077, AI198719, BC017924, BC072447, BP360389, BX649090, DA695719
    Consensus CDS
    CCDS3757.1
    UniProtKB/Swiss-Prot
    O15327, Q2TAI2, Q5XLE7, Q6IN59, Q6PJB4
    UniProtKB/TrEMBL
    D6RJC3
    Related
    ENSP00000262992.4, ENST00000262992.9
    Conserved Domains (1) summary
    cd04048
    Location:39 → 175
    C2A_Copine; C2 domain first repeat in Copine

  2. NM_001331040.1 → NP_001317969.1  inositol polyphosphate 4-phosphatase type II isoform 2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and includes an alternate 3' terminal exon, compared to variant 1, resulting in a novel 3' coding region and novel 3' UTR. It encodes isoform 2 which has a distinct C-terminus and is longer than isoform 1.
    Source sequence(s)
    AC108077, BC072447, BG708971, BX649090, DA695719, DB555643
    Consensus CDS
    CCDS82958.1
    UniProtKB/TrEMBL
    D6RJC3, E7EQN9
    Related
    ENSP00000422793.1, ENST00000509777.5
    Conserved Domains (1) summary
    cd04048
    Location:39 → 175
    C2A_Copine; C2 domain first repeat in Copine

  3. NM_001385334.1 → NP_001372263.1  inositol polyphosphate 4-phosphatase type II isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077, AC139720
    Consensus CDS
    CCDS3757.1
    UniProtKB/Swiss-Prot
    O15327, Q2TAI2, Q5XLE7, Q6IN59, Q6PJB4
    UniProtKB/TrEMBL
    D6RJC3
    Conserved Domains (1) summary
    cd04048
    Location:39 → 175
    C2A_Copine; C2 domain first repeat in Copine

  4. NM_001385335.1 → NP_001372264.1  inositol polyphosphate 4-phosphatase type II isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC093885, AC108060, AC108077, AC139720
    Consensus CDS
    CCDS82958.1
    UniProtKB/TrEMBL
    D6RJC3, E7EQN9
    Conserved Domains (1) summary
    cd04048
    Location:39 → 175
    C2A_Copine; C2 domain first repeat in Copine

  5. NM_001385336.1 → NP_001372265.1  inositol polyphosphate 4-phosphatase type II isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC093885, AC108060, AC108077, AC138657, AC139720
    Consensus CDS
    CCDS3757.1
    UniProtKB/Swiss-Prot
    O15327, Q2TAI2, Q5XLE7, Q6IN59, Q6PJB4
    UniProtKB/TrEMBL
    D6RJC3
    Conserved Domains (1) summary
    cd04048
    Location:39 → 175
    C2A_Copine; C2 domain first repeat in Copine

  6. NM_001385337.1 → NP_001372266.1  inositol polyphosphate 4-phosphatase type II isoform 12

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC093885, AC108060, AC108077, AC138657, AC139720
    Conserved Domains (1) summary
    cd04048
    Location:39 → 175
    C2A_Copine; C2 domain first repeat in Copine

  7. NM_001385338.1 → NP_001372267.1  inositol polyphosphate 4-phosphatase type II isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077, AC139720
    Consensus CDS
    CCDS3757.1
    UniProtKB/Swiss-Prot
    O15327, Q2TAI2, Q5XLE7, Q6IN59, Q6PJB4
    UniProtKB/TrEMBL
    D6RJC3
    Conserved Domains (1) summary
    cd04048
    Location:39 → 175
    C2A_Copine; C2 domain first repeat in Copine

  8. NM_001385339.1 → NP_001372268.1  inositol polyphosphate 4-phosphatase type II isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077, AC139720
    UniProtKB/TrEMBL
    D6RJC3
    Conserved Domains (1) summary
    cd04048
    Location:39 → 175
    C2A_Copine; C2 domain first repeat in Copine

  9. NM_001385340.1 → NP_001372269.1  inositol polyphosphate 4-phosphatase type II isoform 14

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077, AC139720
    Conserved Domains (1) summary
    cd04048
    Location:39 → 175
    C2A_Copine; C2 domain first repeat in Copine

  10. NM_001385341.1 → NP_001372270.1  inositol polyphosphate 4-phosphatase type II isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077, AC139720
    Consensus CDS
    CCDS3757.1
    UniProtKB/Swiss-Prot
    O15327, Q2TAI2, Q5XLE7, Q6IN59, Q6PJB4
    UniProtKB/TrEMBL
    D6RJC3
    Conserved Domains (1) summary
    cd04048
    Location:39 → 175
    C2A_Copine; C2 domain first repeat in Copine

  11. NM_001385342.1 → NP_001372271.1  inositol polyphosphate 4-phosphatase type II isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077, AC139720
    Consensus CDS
    CCDS3757.1
    UniProtKB/Swiss-Prot
    O15327, Q2TAI2, Q5XLE7, Q6IN59, Q6PJB4
    UniProtKB/TrEMBL
    D6RJC3
    Conserved Domains (1) summary
    cd04048
    Location:39 → 175
    C2A_Copine; C2 domain first repeat in Copine

  12. NM_001385343.1 → NP_001372272.1  inositol polyphosphate 4-phosphatase type II isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077, AC139720
    UniProtKB/TrEMBL
    D6RJC3
    Conserved Domains (1) summary
    cd04048
    Location:39 → 175
    C2A_Copine; C2 domain first repeat in Copine

  13. NM_001385344.1 → NP_001372273.1  inositol polyphosphate 4-phosphatase type II isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077, AC139720
    Consensus CDS
    CCDS3757.1
    UniProtKB/Swiss-Prot
    O15327, Q2TAI2, Q5XLE7, Q6IN59, Q6PJB4
    UniProtKB/TrEMBL
    D6RJC3
    Conserved Domains (1) summary
    cd04048
    Location:39 → 175
    C2A_Copine; C2 domain first repeat in Copine

  14. NM_001385347.1 → NP_001372276.1  inositol polyphosphate 4-phosphatase type II isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077, AC139720
    UniProtKB/TrEMBL
    D6RJC3
    Conserved Domains (1) summary
    cd04048
    Location:39 → 175
    C2A_Copine; C2 domain first repeat in Copine

  15. NM_001385348.1 → NP_001372277.1  inositol polyphosphate 4-phosphatase type II isoform 4

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077, AC139720
    UniProtKB/TrEMBL
    D6RJC3
    Conserved Domains (1) summary
    cd04048
    Location:39 → 175
    C2A_Copine; C2 domain first repeat in Copine

  16. NM_001385350.1 → NP_001372279.1  inositol polyphosphate 4-phosphatase type II isoform 10

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077
    UniProtKB/TrEMBL
    B7Z4Z0

  17. NM_001385351.1 → NP_001372280.1  inositol polyphosphate 4-phosphatase type II isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077
    UniProtKB/TrEMBL
    B7Z4Z0

  18. NM_001385357.1 → NP_001372286.1  inositol polyphosphate 4-phosphatase type II isoform 17

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077
    UniProtKB/TrEMBL
    B7Z4Z0

  19. NM_001385362.1 → NP_001372291.1  inositol polyphosphate 4-phosphatase type II isoform 18

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077
    UniProtKB/TrEMBL
    B7Z4Z0

  20. NM_001385379.1 → NP_001372308.1  inositol polyphosphate 4-phosphatase type II isoform 10

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077
    UniProtKB/TrEMBL
    B7Z4Z0

  21. NM_001385380.1 → NP_001372309.1  inositol polyphosphate 4-phosphatase type II isoform 13

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077
    UniProtKB/TrEMBL
    B7Z4Z0

  22. NM_001385381.1 → NP_001372310.1  inositol polyphosphate 4-phosphatase type II isoform 11

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077
    UniProtKB/TrEMBL
    B7Z4Z0

  23. NM_001385382.1 → NP_001372311.1  inositol polyphosphate 4-phosphatase type II isoform 9

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077
    UniProtKB/TrEMBL
    B7Z4Z0

  24. NM_001385383.1 → NP_001372312.1  inositol polyphosphate 4-phosphatase type II isoform 10

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077
    UniProtKB/TrEMBL
    B7Z4Z0

  25. NM_001385450.1 → NP_001372379.1  inositol polyphosphate 4-phosphatase type II isoform 15

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077
    UniProtKB/TrEMBL
    B7Z4Z0

  26. NM_001385452.1 → NP_001372381.1  inositol polyphosphate 4-phosphatase type II isoform 16

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077
    UniProtKB/TrEMBL
    B7Z4Z0

  27. NM_001385454.1 → NP_001372383.1  inositol polyphosphate 4-phosphatase type II isoform 19

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077

  28. NM_001385455.1 → NP_001372384.1  inositol polyphosphate 4-phosphatase type II isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077
    UniProtKB/TrEMBL
    B7Z4Z0

  29. NM_001385457.1 → NP_001372386.1  inositol polyphosphate 4-phosphatase type II isoform 10

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108077
    UniProtKB/TrEMBL
    B7Z4Z0

  30. NM_001385458.1 → NP_001372387.1  inositol polyphosphate 4-phosphatase type II isoform 17

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108077
    UniProtKB/TrEMBL
    B7Z4Z0

  31. NM_001385459.1 → NP_001372388.1  inositol polyphosphate 4-phosphatase type II isoform 7

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108077
    UniProtKB/TrEMBL
    B7Z4Z0, E9PCZ3
    Related
    ENSP00000426207.2, ENST00000511838.6

  32. NM_001385460.1 → NP_001372389.1  inositol polyphosphate 4-phosphatase type II isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108077
    UniProtKB/TrEMBL
    E9PHC0
    Related
    ENSP00000421065.1, ENST00000514525.1

  33. NM_001385461.1 → NP_001372390.1  inositol polyphosphate 4-phosphatase type II isoform 10

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077
    UniProtKB/TrEMBL
    B7Z4Z0

  34. NM_003866.3 → NP_003857.2  inositol polyphosphate 4-phosphatase type II isoform 1

    See identical proteins and their annotated locations for NP_003857.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the shorter isoform (1). Variants 1 and 2 encode the same isoform (1).
    Source sequence(s)
    AC108077, AI198719, BC017924, BC072447, BX649090, DA695719
    Consensus CDS
    CCDS3757.1
    UniProtKB/Swiss-Prot
    O15327, Q2TAI2, Q5XLE7, Q6IN59, Q6PJB4
    UniProtKB/TrEMBL
    D6RJC3
    Related
    ENSP00000425487.1, ENST00000513000.5
    Conserved Domains (1) summary
    cd04048
    Location:39 → 175
    C2A_Copine; C2 domain first repeat in Copine

RNA

  1. NR_169599.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077

  2. NR_169614.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077

  3. NR_169615.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077, AC139720

  4. NR_169616.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077

  5. NR_169617.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077, AC139720

  6. NR_169618.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077

  7. NR_169619.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077

  8. NR_169623.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077

  9. NR_169624.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC093860, AC108060, AC108077

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    142023160..142846535 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047416359.1 → XP_047272315.1  inositol polyphosphate 4-phosphatase type II isoform X3

    UniProtKB/Swiss-Prot
    O15327, Q2TAI2, Q5XLE7, Q6IN59, Q6PJB4

  2. XM_047416356.1 → XP_047272312.1  inositol polyphosphate 4-phosphatase type II isoform X3

    UniProtKB/Swiss-Prot
    O15327, Q2TAI2, Q5XLE7, Q6IN59, Q6PJB4

  3. XM_047416357.1 → XP_047272313.1  inositol polyphosphate 4-phosphatase type II isoform X3

    UniProtKB/Swiss-Prot
    O15327, Q2TAI2, Q5XLE7, Q6IN59, Q6PJB4

  4. XM_047416358.1 → XP_047272314.1  inositol polyphosphate 4-phosphatase type II isoform X3

    UniProtKB/Swiss-Prot
    O15327, Q2TAI2, Q5XLE7, Q6IN59, Q6PJB4
    Related
    ENSP00000423954.1, ENST00000508116.5

  5. XM_047416362.1 → XP_047272318.1  inositol polyphosphate 4-phosphatase type II isoform X5

  6. XM_047416361.1 → XP_047272317.1  inositol polyphosphate 4-phosphatase type II isoform X5

  7. XM_047416360.1 → XP_047272316.1  inositol polyphosphate 4-phosphatase type II isoform X4

  8. XM_011532391.3 → XP_011530693.1  inositol polyphosphate 4-phosphatase type II isoform X1

    See identical proteins and their annotated locations for XP_011530693.1

    UniProtKB/TrEMBL
    D6RJC3
    Conserved Domains (1) summary
    cd04048
    Location:39 → 175
    C2A_Copine; C2 domain first repeat in Copine

  9. XM_024454274.2 → XP_024310042.1  inositol polyphosphate 4-phosphatase type II isoform X2

    UniProtKB/TrEMBL
    D6RJC3, E7EQN9
    Conserved Domains (1) summary
    cd04048
    Location:39 → 175
    C2A_Copine; C2 domain first repeat in Copine

  10. XM_047416354.1 → XP_047272310.1  inositol polyphosphate 4-phosphatase type II isoform X2

    UniProtKB/TrEMBL
    E7EQN9
    Related
    ENSP00000427250.1, ENST00000510812.5

  11. XM_024454273.2 → XP_024310041.1  inositol polyphosphate 4-phosphatase type II isoform X1

    UniProtKB/TrEMBL
    D6RJC3
    Conserved Domains (1) summary
    cd04048
    Location:39 → 175
    C2A_Copine; C2 domain first repeat in Copine

  12. XM_047416352.1 → XP_047272308.1  inositol polyphosphate 4-phosphatase type II isoform X2

    UniProtKB/TrEMBL
    E7EQN9

  13. XM_047416353.1 → XP_047272309.1  inositol polyphosphate 4-phosphatase type II isoform X2

    UniProtKB/TrEMBL
    E7EQN9

  14. XM_017008797.2 → XP_016864286.1  inositol polyphosphate 4-phosphatase type II isoform X6

    UniProtKB/TrEMBL
    E9PHC0

  15. XM_017008798.2 → XP_016864287.1  inositol polyphosphate 4-phosphatase type II isoform X8

    UniProtKB/TrEMBL
    B7Z4Z0

  16. XM_047416363.1 → XP_047272319.1  inositol polyphosphate 4-phosphatase type II isoform X7

  17. XM_047416365.1 → XP_047272321.1  inositol polyphosphate 4-phosphatase type II isoform X9

  18. XM_047416368.1 → XP_047272324.1  inositol polyphosphate 4-phosphatase type II isoform X11

  19. XM_047416367.1 → XP_047272323.1  inositol polyphosphate 4-phosphatase type II isoform X11

  20. XM_047416366.1 → XP_047272322.1  inositol polyphosphate 4-phosphatase type II isoform X10

RNA

  1. XR_007057981.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    145340544..146163746 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O15327.4 GenPept UniProtKB/Swiss-Prot:O15327

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