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plcB phospholipase C [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 880904, updated on 24-Aug-2024

Summary

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Gene symbol
plcB
Gene description
phospholipase C
Locus tag
PA0026
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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Genomic context

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Sequence:
NC_002516.2 (27646..28632)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene coproporphyrinogen III oxidase Neighboring gene shikimate dehydrogenase Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene sulfate transporter

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. End-products diacylglycerol and ceramide modulate membrane fusion induced by a phospholipase C/sphingomyelinase from Pseudomonas aeruginosa. Ibarguren M, et al. Biochim Biophys Acta, 2010 Jan. PMID 19891956, Free PMC Article
  2. A novel extracellular phospholipase C of Pseudomonas aeruginosa is required for phospholipid chemotaxis. Barker AP, et al. Mol Microbiol, 2004 Aug. PMID 15306013
  3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
  5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data show that both diacylglycerol and ceramide have different effects on the ENZYME activity, DAG enhancing enzyme-induced vesicle aggregation and fusion, Cer inhibiting the hydrolytic activity.
    Title: End-products diacylglycerol and ceramide modulate membrane fusion induced by a phospholipase C/sphingomyelinase from Pseudomonas aeruginosa.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by PseudoCAP

Function Evidence Code Pubs
enables lipase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables phospholipase C activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within chemotaxis IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within protein secretion by the type II secretion system IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within protein transport by the Sec complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
phospholipase C
NP_248716.1
  • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    27646..28632
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_248716.1 phospholipase C [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_248716.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    Q9I7A4
    Conserved Domains (1) summary
    cd11009
    Location:120 → 317
    Zn_dep_PLPC; Zinc dependent phospholipase C (alpha toxin)
Nucleotide Protein
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