U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

hcp1 [ Pseudomonas aeruginosa PAO1 ]

Gene ID: 879446, updated on 11-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
hcp1
Primary source
PseudoCap:PA0085
Locus tag
PA0085
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pseudomonas aeruginosa PAO1 (strain: PAO1)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_002516.2 (103350..103838)

NC_002516.2Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene hypothetical protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_002516.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Genetically encoded photochemical covalent crosslinking within the Hcp-1 self-assembling bacterial secretion machinery. Antonczak AK, et al. Amino Acids, 2018 May. PMID 29307074
  2. Haemolysin coregulated protein is an exported receptor and chaperone of type VI secretion substrates. Silverman JM, et al. Mol Cell, 2013 Sep 12. PMID 23954347, Free PMC Article
  3. Type VI secretion system in Pseudomonas aeruginosa: secretion and multimerization of VgrG proteins. Hachani A, et al. J Biol Chem, 2011 Apr 8. PMID 21325275, Free PMC Article
  4. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
  5. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The results demonstrate the choice and role of genetically encoded tools applied to complicated biological processes such as self-assembly and also suggested some structural dynamics of the Hcp-1 protein not obvious from crystallographic structures.
    Title: Genetically encoded photochemical covalent crosslinking within the Hcp-1 self-assembling bacterial secretion machinery.
  2. Hcp1 protein is an exported receptor and chaperone of type VI bacterial secretion substrates.Hcp1 is a chaperone required for the intracellular accumulation of Tse2.
    Title: Haemolysin coregulated protein is an exported receptor and chaperone of type VI secretion substrates.
  3. Hcp1 secretion requires either VgrG1a or VgrG1c, which may act independently to puncture the bacterial envelope and give Hcp1 access to the surface.
    Title: Type VI secretion system in Pseudomonas aeruginosa: secretion and multimerization of VgrG proteins.
  4. current data indicating that the HSI-I locus actively secretes Hcp1 during chronic infection of CF patients, collectively suggest a role for HSI-I in chronic P. aeruginosa infections
    Title: A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

General protein information

Go to the top of the page Help
Preferred Names
protein secretion apparatus assembly protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_002516.2 Reference assembly

    Range
    103350..103838
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_248775.1 protein secretion apparatus assembly protein [Pseudomonas aeruginosa PAO1]

    See identical proteins and their annotated locations for NP_248775.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2R3IPV7
    Conserved Domains (1) summary
    pfam05638
    Location:6 → 136
    T6SS_HCP; Type VI secretion system effector, Hcp
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9I747.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials