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AVT2 Avt2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 856645, updated on 4-Jan-2025

Summary

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Official Symbol
AVT2
Official Full Name
Avt2p
Primary source
SGD:S000000790
Locus tag
YEL064C
See related
AllianceGenome:SGD:S000000790; FungiDB:YEL064C; VEuPathDB:YEL064C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Located in endoplasmic reticulum. Orthologous to human SLC38A11 (solute carrier family 38 member 11). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See AVT2 in Genome Data Viewer
Location:
chromosome: V
Exon count:
1
Sequence:
Chromosome: V; NC_001137.3 (29797..31239, complement)

Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene D-amino-acid N-acetyltransferase Neighboring gene siderophore transporter Neighboring gene arginine permease CAN1 Neighboring gene nitrogen permease regulating protein NPR2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001137.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A family of yeast proteins mediating bidirectional vacuolar amino acid transport. Russnak R, et al. J Biol Chem, 2001 Jun 29. PMID 11274162
  2. Vacuolar amino acid transporters upregulated by exogenous proline and involved in cellular localization of proline in Saccharomyces cerevisiae. Nishida I, et al. J Gen Appl Microbiol, 2016 Jul 14. PMID 27246536
  3. Bootstrapping the interactome: unsupervised identification of protein complexes in yeast. Friedel CC, et al. J Comput Biol, 2009 Aug. PMID 19630542
  4. The yeast oligopeptide transporter Opt2 is localized to peroxisomes and affects glutathione redox homeostasis. Elbaz-Alon Y, et al. FEMS Yeast Res, 2014 Nov. PMID 25130273
  5. The phox homology (PX) domain protein interaction network in yeast. Vollert CS, et al. Mol Cell Proteomics, 2004 Nov. PMID 15263065

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables L-amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in L-alpha-amino acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in amino acid transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in vacuolar membrane IEA
Inferred from Electronic Annotation
more info
  
located_in vacuole IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Avt2p
NP_010850.1
  • Putative transporter; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001137.3 Reference assembly

    Range
    29797..31239 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178879.1 → NP_010850.1  TPA: Avt2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010850.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D3DLI6, P39981, Q2VQX2
    UniProtKB/TrEMBL
    A6ZQN7, N1P536
    Conserved Domains (1) summary
    pfam01490
    Location:65 → 467
    Aa_trans; Transmembrane amino acid transporter protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P39981.1

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