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KTR6 putative mannosyltransferase [ Saccharomyces cerevisiae S288C ]

Gene ID: 856054, updated on 4-Jan-2025

Summary

Official Symbol
KTR6
Official Full Name
putative mannosyltransferase
Primary source
SGD:S000005974
Locus tag
YPL053C
See related
AllianceGenome:SGD:S000005974; FungiDB:YPL053C; VEuPathDB:YPL053C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
MNN6
Summary
Enables mannosylphosphate transferase activity. Involved in fungal-type cell wall organization and protein N-linked glycosylation. Acts upstream of or within endoplasmic reticulum to Golgi vesicle-mediated transport. Located in endoplasmic reticulum and membrane. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

See KTR6 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (457118..458458, complement)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Lge1p Neighboring gene Lee1p Neighboring gene Oaz1p Neighboring gene Arf family GTPase ARL3

Pathways from PubChem

Interactions

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables alpha-1,2-mannosyltransferase activity  
enables glycosyltransferase activity  
enables mannosylphosphate transferase activity PubMed 
enables mannosyltransferase activity  
Component Evidence Code Pubs
is_active_in Golgi apparatus  
located_in endoplasmic reticulum PubMed 
located_in fungal-type vacuole PubMed 
located_in membrane PubMed 
located_in membrane  

General protein information

Preferred Names
putative mannosyltransferase
NP_015272.1
  • Probable mannosylphosphate transferase; involved in the synthesis of core oligosaccharides in protein glycosylation pathway; facilitates the exit of Mnn4p from the ER via COPII-coated vesicles; member of the KRE2/MNT1 mannosyltransferase family; KTR6 has a paralog, KRE2, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    457118..458458 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183867.1 → NP_015272.1  TPA: putative mannosyltransferase [Saccharomyces cerevisiae S288C]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W3W1, P54070
    UniProtKB/TrEMBL
    A6ZWJ5, B3LL14, C7GU02, C8ZIX7, G2WPC5
    Conserved Domains (1) summary
    COG5020
    Location:7 → 443
    KTR1; Mannosyltransferase [Carbohydrate transport and metabolism]
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