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uncharacterized protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 855885, updated on 4-Jan-2025

Summary

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Official Full Name
uncharacterized protein
Primary source
SGD:S000006137
Locus tag
YPL216W
See related
AllianceGenome:SGD:S000006137; FungiDB:YPL216W; VEuPathDB:YPL216W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to be involved in subtelomeric heterochromatin formation. Predicted to be located in chromatin and chromosome, telomeric region. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (143821..147129)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Arf family GTPase SAR1 Neighboring gene GTPase BMS1 Neighboring gene Cbp3p Neighboring gene bifunctional hydroxyethylthiazole kinase/thiamine-phosphate diphosphorylase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001148.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Comprehensive characterization of the Hsp70 interactome reveals novel client proteins and interactions mediated by posttranslational modifications. Nitika, et al. PLoS Biol, 2022 Oct. PMID 36269765, Free PMC Article
  2. Functional profiling of the Saccharomyces cerevisiae genome. Giaever G, et al. Nature, 2002 Jul 25. PMID 12140549
  3. Coiled-coil networking shapes cell molecular machinery. Wang Y, et al. Mol Biol Cell, 2012 Oct. PMID 22875988, Free PMC Article
  4. Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control. Gallina I, et al. Nat Commun, 2015 Mar 30. PMID 25817432, Free PMC Article
  5. The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI. Bussey H, et al. Nature, 1997 May 29. PMID 9169875

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in chromatin organization IEA
Inferred from Electronic Annotation
more info
  
involved_in subtelomeric heterochromatin formation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in chromatin IEA
Inferred from Electronic Annotation
more info
  
located_in chromosome, telomeric region IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
NP_015108.1
  • hypothetical protein; not an essential gene; YPL216W has a paralog, ITC1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    143821..147129
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184030.1 → NP_015108.1  TPA: uncharacterized protein YPL216W [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015108.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W3F4, Q08964
    UniProtKB/TrEMBL
    C7GN43
    Conserved Domains (5) summary
    smart00571
    Location:375 → 435
    DDT; domain in different transcription and chromosome remodeling factors
    pfam10537
    Location:26 → 124
    WAC_Acf1_DNA_bd; ATP-utilizing chromatin assembly and remodelling N-terminal
    pfam15612
    Location:626 → 667
    WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
    pfam15613
    Location:750 → 793
    WHIM2; WSTF, HB1, Itc1p, MBD9 motif 2
    pfam15614
    Location:885 → 923
    WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q08964.1

Gene LinkOut

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