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HFI1 Hfi1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 855821, updated on 4-Jan-2025

Summary

Official Symbol
HFI1
Official Full Name
Hfi1p
Primary source
SGD:S000006175
Locus tag
YPL254W
See related
AllianceGenome:SGD:S000006175; FungiDB:YPL254W; VEuPathDB:YPL254W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
ADA1; GAN1; SRM12; SUP110
Summary
Enables transcription coactivator activity. Involved in chromatin organization and transcription by RNA polymerase II. Part of SAGA complex and SLIK (SAGA-like) complex. Orthologous to human TADA1 (transcriptional adaptor 1). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

See HFI1 in Genome Data Viewer
Location:
chromosome: XVI
Exon count:
1
Sequence:
Chromosome: XVI; NC_001148.4 (69485..70951)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene cyclin CLN2 Neighboring gene Bbp1p Neighboring gene Vik1p Neighboring gene adrenodoxin

Bibliography

Interactions

General gene information

Gene Ontology Provided by SGD

Component Evidence Code Pubs
part_of SAGA complex  
part_of SAGA complex PubMed 
part_of SAGA-type complex  
part_of SLIK (SAGA-like) complex PubMed 
located_in nucleus  

General protein information

Preferred Names
Hfi1p
NP_015069.1
  • Adaptor protein required for structural integrity of the SAGA complex; a histone acetyltransferase-coactivator complex that is involved in global regulation of gene expression through acetylation and transcription functions

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    69485..70951
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184068.1 → NP_015069.1  TPA: Hfi1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015069.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W3B7, O00039, Q02813, Q12060
    UniProtKB/TrEMBL
    A6ZW02, B3LKH8, B5VST3, C7GTR1, C8ZIC4, N1NVY2
    Conserved Domains (1) summary
    pfam12767
    Location:60 → 316
    SAGA-Tad1; Transcriptional regulator of RNA polII, SAGA, subunit
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