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uncharacterized protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 855755, updated on 4-Jan-2025

Summary

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Official Full Name
uncharacterized protein
Primary source
SGD:S000005304
Locus tag
YNR021W
See related
AllianceGenome:SGD:S000005304; FungiDB:YNR021W; VEuPathDB:YNR021W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable calcium ion binding activity. Predicted to be involved in endoplasmic reticulum calcium ion homeostasis. Located in endoplasmic reticulum. Orthologous to human CCDC47 (coiled-coil domain containing 47). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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Location:
chromosome: XIV
Exon count:
1
Sequence:
Chromosome: XIV; NC_001146.8 (668377..669591)

Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene sterol acyltransferase Neighboring gene putative metalloprotease Neighboring gene mitochondrial 54S ribosomal protein MRPL50 Neighboring gene Snf12p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001146.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation. Zhao R, et al. J Cell Biol, 2008 Feb 11. PMID 18268103, Free PMC Article
  2. A complex of Cox4 and mitochondrial Hsp70 plays an important role in the assembly of the cytochrome c oxidase. Böttinger L, et al. Mol Biol Cell, 2013 Sep. PMID 23864706, Free PMC Article
  3. The SND proteins constitute an alternative targeting route to the endoplasmic reticulum. Aviram N, et al. Nature, 2016 Nov 30. PMID 27905431, Free PMC Article
  4. Integrating high-throughput genetic interaction mapping and high-content screening to explore yeast spindle morphogenesis. Vizeacoumar FJ, et al. J Cell Biol, 2010 Jan 11. PMID 20065090, Free PMC Article
  5. A conserved endoplasmic reticulum membrane protein complex (EMC) facilitates phospholipid transfer from the ER to mitochondria. Lahiri S, et al. PLoS Biol, 2014 Oct. PMID 25313861, Free PMC Article

See all (43) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables calcium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in endoplasmic reticulum calcium ion homeostasis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum HDA PubMed 
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
NP_014418.3
  • hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YNR021W is not an essential gene

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001146.8 Reference assembly

    Range
    668377..669591
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001183198.3 → NP_014418.3  TPA: uncharacterized protein YNR021W [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_014418.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W1J6, P53723
    UniProtKB/TrEMBL
    A6ZS95, B3LPM2, C8ZFP8, N1NY64
    Conserved Domains (1) summary
    pfam07946
    Location:44 → 394
    DUF1682; Protein of unknown function (DUF1682)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P53723.3

Gene LinkOut

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