SGA1 glucan 1,4-alpha-glucosidase [Saccharomyces cerevisiae S288C] - Gene

Summary

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Official Symbol: SGA1
Official Full Name: glucan 1,4-alpha-glucosidase
Primary source: SGD:S000001361
Locus tag: YIL099W
See related: AllianceGenome:SGD:S000001361; FungiDB:YIL099W; VEuPathDB:YIL099W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables glucan 1,4-alpha-glucosidase activity. Involved in glycogen catabolic process. Located in fungal-type vacuole. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See SGA1 in Genome Data Viewer

Location:: chromosome: IX

Exon count:: 1

Sequence:: Chromosome: IX; NC_001141.2 (178004..179653)

Chromosome IX - NC_001141.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_001141.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

Gene Ontology Provided by SGD

Function	Evidence Code	Pubs
enables glucan 1,4-alpha-glucosidase activity	IDA Inferred from Direct Assay more info	PubMed
enables glucan 1,4-alpha-glucosidase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity, acting on glycosyl bonds	IEA Inferred from Electronic Annotation more info
enables hydrolase activity, hydrolyzing O-glycosyl compounds	IBA Inferred from Biological aspect of Ancestor more info
enables hydrolase activity, hydrolyzing O-glycosyl compounds	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in glycogen catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in polysaccharide catabolic process	IEA Inferred from Electronic Annotation more info
involved_in polysaccharide metabolic process	IEA Inferred from Electronic Annotation more info
involved_in sporulation resulting in formation of a cellular spore	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in fungal-type vacuole	HDA more info	PubMed
is_active_in fungal-type vacuole	IBA Inferred from Biological aspect of Ancestor more info
located_in fungal-type vacuole	IDA Inferred from Direct Assay more info	PubMed
located_in prospore membrane	HDA more info	PubMed

General protein information

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Preferred Names: glucan 1,4-alpha-glucosidase

NP_012167.3

EC 3.2.1.3

Intracellular sporulation-specific glucoamylase; involved in glycogen degradation; induced during starvation of a/a diploids late in sporulation, but dispensable for sporulation

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001141.2 Reference assembly

Range

178004..179653

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001179447.3 → NP_012167.3 TPA: glucan 1,4-alpha-glucosidase [Saccharomyces cerevisiae S288C]

See identical proteins and their annotated locations for NP_012167.3

Status: REVIEWED

UniProtKB/Swiss-Prot

D6VVI8, P08019, Q07070

UniProtKB/TrEMBL

C7GKM6, N1P9B4

Conserved Domains (1) summary

COG3387
Location:1 → 548

SGA1; Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family [Carbohydrate transport and metabolism]