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HOS4 Hos4p [ Saccharomyces cerevisiae S288C ]

Gene ID: 854694, updated on 4-Jan-2025

Summary

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Official Symbol
HOS4
Official Full Name
Hos4p
Primary source
SGD:S000001374
Locus tag
YIL112W
See related
AllianceGenome:SGD:S000001374; FungiDB:YIL112W; VEuPathDB:YIL112W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in chromatin remodeling. Part of Set3 complex. [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See HOS4 in Genome Data Viewer
Location:
chromosome: IX
Exon count:
1
Sequence:
Chromosome: IX; NC_001141.2 (151595..154846)

Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene putative porin POR2 Neighboring gene mitogen-activated protein kinase tyrosine protein phosphatase SDP1 Neighboring gene cytochrome c oxidase subunit Vb Neighboring gene protein-histidine N-methyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001141.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural and functional analysis of the SET3 histone deacetylase complex. Reyes AA, et al. Acta Crystallogr F Struct Biol Commun, 2022 Mar 1. PMID 35234136, Free PMC Article
  2. Cyclophilin A is localized to the nucleus and controls meiosis in Saccharomyces cerevisiae. Arévalo-Rodríguez M, et al. Eukaryot Cell, 2005 Jan. PMID 15643056, Free PMC Article
  3. The Set3 Complex Antagonizes the MYST Acetyltransferase Esa1 in the DNA Damage Response. Torres-Machorro AL, et al. Mol Cell Biol, 2015 Nov. PMID 26303527, Free PMC Article
  4. Dimethylation of H3K4 by Set1 recruits the Set3 histone deacetylase complex to 5' transcribed regions. Kim T, et al. Cell, 2009 Apr 17. PMID 19379692, Free PMC Article
  5. Deciphering protein complexes and protein interaction networks by tandem affinity purification and mass spectrometry: analytical perspective. Shevchenko A, et al. Mol Cell Proteomics, 2002 Mar. PMID 12096120

See all (50) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in chromatin remodeling IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
part_of Set3 complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Hos4p
NP_012154.1
  • Subunit of the Set3 complex; complex is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001141.2 Reference assembly

    Range
    151595..154846
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179460.1 → NP_012154.1  TPA: Hos4p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012154.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VVH5, P40480
    UniProtKB/TrEMBL
    N1P4E2
    Conserved Domains (2) summary
    sd00045
    Location:330 → 361
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:334 → 429
    Ank_2; Ankyrin repeats (3 copies)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40480.1

Gene LinkOut

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