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YET1 Yet1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 853800, updated on 4-Jan-2025

Summary

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Official Symbol
YET1
Official Full Name
Yet1p
Primary source
SGD:S000001548
Locus tag
YKL065C
See related
AllianceGenome:SGD:S000001548; FungiDB:YKL065C; VEuPathDB:YKL065C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and protein localization to endoplasmic reticulum exit site. Located in endoplasmic reticulum. Orthologous to human BCAP29 (B cell receptor associated protein 29). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See YET1 in Genome Data Viewer
Location:
chromosome: XI
Exon count:
1
Sequence:
Chromosome: XI; NC_001143.9 (316437..317057, complement)

Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene nucleoside diphosphate kinase Neighboring gene Dpc7p Neighboring gene putative Mg(2+) transporter MNR2 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001143.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Yet1p and Yet3p, the yeast homologs of BAP29 and BAP31, interact with the endoplasmic reticulum translocation apparatus and are required for inositol prototrophy. Wilson JD, et al. J Biol Chem, 2010 Jun 11. PMID 20378542, Free PMC Article
  2. Yet1p-Yet3p interacts with Scs2p-Opi1p to regulate ER localization of the Opi1p repressor. Wilson JD, et al. Mol Biol Cell, 2011 May. PMID 21372176, Free PMC Article
  3. Genome-wide SWAp-Tag yeast libraries for proteome exploration. Weill U, et al. Nat Methods, 2018 Aug. PMID 29988094, Free PMC Article
  4. ER-to-plasma membrane tethering proteins regulate cell signaling and ER morphology. Manford AG, et al. Dev Cell, 2012 Dec 11. PMID 23237950
  5. Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Fleischer TC, et al. Genes Dev, 2006 May 15. PMID 16702403, Free PMC Article

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. show that the Yet1p-Yet3p complex acts in derepression of INO1 through physical association with Scs2p-Opi1p
    Title: Yet1p-Yet3p interacts with Scs2p-Opi1p to regulate ER localization of the Opi1p repressor.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in protein localization to endoplasmic reticulum exit site IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum HDA PubMed 
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Yet1p
NP_012858.2
  • Endoplasmic reticulum transmembrane protein; may interact with ribosomes, based on co-purification experiments; homolog of human BAP31 protein; YET1 has a paralog, YET2, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001143.9 Reference assembly

    Range
    316437..317057 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179631.2 → NP_012858.2  TPA: Yet1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_012858.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VXM2, P35723, Q6Q5G9
    UniProtKB/TrEMBL
    A6ZZQ1, B3LR26, B5VM92, C7GP06, C8ZCA7, G2WHW7, N1P7U3
    Conserved Domains (1) summary
    COG5374
    Location:14 → 206
    COG5374; Uncharacterized conserved protein [Function unknown]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P35723.2

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