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eukaryotic translation initiation factor 2 (eIF-2) family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 844015, updated on 18-Sep-2024

Summary

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Official Full Name
eukaryotic translation initiation factor 2 (eIF-2) family protein
Primary source
TAIR:AT1G76810
Locus tag
AT1G76810
See related
Araport:AT1G76810
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F28O16.18; F28O16_18
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Genomic context

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Location:
chromosome: 1
Exon count:
13
Sequence:
Chromosome: 1; NC_003070.9 (28830902..28836748, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene HSP20-like chaperones superfamily protein Neighboring gene O-methyltransferase family protein Neighboring gene Vacuolar iron transporter (VIT) family protein Neighboring gene eukaryotic translation initiation factor 2 (eIF-2) family protein Neighboring gene F-box and associated interaction domains-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mutations in eIF5B Confer Thermosensitive and Pleiotropic Phenotypes via Translation Defects in Arabidopsis thaliana. Zhang L, et al. Plant Cell, 2017 Aug. PMID 28808135, Free PMC Article
  2. Interactomics of Qa-SNARE in Arabidopsis thaliana. Fujiwara M, et al. Plant Cell Physiol, 2014 Apr. PMID 24556609
  3. Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism. Ito J, et al. J Proteome Res, 2011 Apr 1. PMID 21166475
  4. Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method. Bach-Pages M, et al. Biomolecules, 2020 Apr 24. PMID 32344669, Free PMC Article
  5. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_106331.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables mRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
NOT located_in cytosol RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in mitochondrion HDA PubMed 

General protein information

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Preferred Names
eukaryotic translation initiation factor 2 (eIF-2) family protein
NP_177807.3
  • eukaryotic translation initiation factor 2 (eIF-2) family protein; FUNCTIONS IN: translation factor activity, nucleic acid binding, GTP binding, GTPase activity; LOCATED IN: plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Small GTP-binding protein (InterPro:IPR005225), Translation elongation factor EFTu/EF1A, domain 2 (InterPro:IPR004161), Translation initiation factor 2 related (InterPro:IPR015760), Protein synthesis factor, GTP-binding (InterPro:IPR000795), Translation elongation/initiation factor/Ribosomal, beta-barrel (InterPro:IPR009000); BEST Arabidopsis thaliana protein match is: eukaryotic translation initiation factor 2 (eIF-2) family protein (TAIR:AT1G76720.1); Has 208612 Blast hits to 135501 proteins in 4311 species: Archae - 1435; Bacteria - 54544; Metazoa - 70572; Fungi - 21896; Plants - 9806; Viruses - 724; Other Eukaryotes - 49635 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    28830902..28836748 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_106331.5 → NP_177807.3  eukaryotic translation initiation factor 2 (eIF-2) family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_177807.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5S9WUZ8, F4I420
    Conserved Domains (5) summary
    cd01887
    Location:706 → 916
    IF2_eIF5B; Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family
    PRK04004
    Location:700 → 1294
    PRK04004; translation initiation factor IF-2; Validated
    pfam11987
    Location:1040 → 1141
    IF-2; Translation-initiation factor 2
    cd03703
    Location:927 → 1037
    aeIF5B_II; Domain II of archaeal and eukaryotic Initiation Factor 5
    cd16266
    Location:1166 → 1260
    IF2_aeIF5B_IV; Domain IV of prokaryotic Initiation Factor 2 and archaeal and eukaryotic Initiation Factor 5
Nucleotide Protein
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