protein tyrosine kinase family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Full Name: protein tyrosine kinase family protein
Primary source: TAIR:AT1G73660
Locus tag: AT1G73660
See related: Araport:AT1G73660
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F25P22.8; F25P22_8; SIS8; SUGAR INSENSITIVE 8
Summary: Encodes a protein with similarity to MAPKKKs. May function as a negative regulator of salt tolerance.
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Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

SIS8, a putative MAPKKK, is a regulator of sugar response in Arabidopsis and interacts with a UDP-glucosyltransferase (UGT72E1) in the nucleus.
Title: SIS8, a putative mitogen-activated protein kinase kinase kinase, regulates sugar-resistant seedling development in Arabidopsis.
The At1g73660 gene coding for a Raf-like MAPKKK, is a negative regulator of salt tolerance.
Title: The genetic locus At1g73660 encodes a putative MAPKKK and negatively regulates salt tolerance in Arabidopsis.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_106025.4

Function	Evidence Code	Pubs
enables MAP kinase kinase kinase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info
enables protein serine/threonine/tyrosine kinase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within response to salt stress	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in stomatal closure	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within sugar mediated signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	HDA more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

NP_177507.1

protein tyrosine kinase family protein; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Ubiquitin interacting motif (InterPro:IPR003903), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT1G18160.1); Has 126827 Blast hits to 124278 proteins in 4857 species: Archae - 98; Bacteria - 13376; Metazoa - 48156; Fungi - 11388; Plants - 33654; Viruses - 503; Other Eukaryotes - 19652 (source: NCBI BLink).

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The following sections contain reference sequences that belong to a specific genome build. Explain