U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PFI tubulin folding cofactor E / Pfifferling (PFI) [ Arabidopsis thaliana (thale cress) ]

Gene ID: 843485, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
PFI
Official Full Name
tubulin folding cofactor E / Pfifferling (PFI)
Primary source
TAIR:AT1G71440
Locus tag
AT1G71440
See related
Araport:AT1G71440
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F3I17.21; F3I17_21; PFIFFERLING; TFC E; TUBULIN-FOLDING COFACTOR E
Summary
Encodes tubulin-folding cofactor E. Mutant embryos consist of one or a few grossly enlarged cells, surrounded by an endosperm that fails to cellularize and contains a few big nuclei.
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See PFI in Genome Data Viewer
Location:
chromosome: 1
Exon count:
15
Sequence:
Chromosome: 1; NC_003070.9 (26921060..26924431, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene Integrase-type DNA-binding superfamily protein Neighboring gene Pentatricopeptide repeat (PPR-like) superfamily protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Mutations in the pilz group genes disrupt the microtubule cytoskeleton and uncouple cell cycle progression from cell division in Arabidopsis embryo and endosperm. Mayer U, et al. Eur J Cell Biol, 1999 Feb. PMID 10099932
  2. The Arabidopsis PILZ group genes encode tubulin-folding cofactor orthologs required for cell division but not cell growth. Steinborn K, et al. Genes Dev, 2002 Apr 15. PMID 11959844, Free PMC Article
  3. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
  4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help
NM_105813.4

Gene Ontology Provided by TAIR

Process Evidence Code Pubs
acts_upstream_of_or_within cytokinesis by cell plate formation IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within embryo development ending in seed dormancy IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 

General protein information

Go to the top of the page Help
Preferred Names
tubulin folding cofactor E / Pfifferling (PFI)
NP_565017.1
  • PFIFFERLING (PFI); INVOLVED IN: tubulin complex assembly, embryo development ending in seed dormancy, cytokinesis; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cytoskeleton-associated protein, CAP-Gly (InterPro:IPR000938); Has 7270 Blast hits to 6366 proteins in 489 species: Archae - 4; Bacteria - 1949; Metazoa - 3435; Fungi - 492; Plants - 819; Viruses - 0; Other Eukaryotes - 571 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    26921060..26924431 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_105813.4 → NP_565017.1  tubulin folding cofactor E / Pfifferling (PFI) [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_565017.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8GRL7, Q8L405, Q9C9I1
    UniProtKB/TrEMBL
    A0A178VZZ6, A0A5S9WRG1, A0A654EN45
    Conserved Domains (4) summary
    smart01052
    Location:12 → 81
    CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
    sd00033
    Location:136 → 161
    LRR_RI; leucine-rich repeat [structural motif]
    cd17044
    Location:446 → 528
    Ubl_TBCE; ubiquitin-like (Ubl) domain found in tubulin-folding cofactor E (TBCE) and similar proteins
    cd21340
    Location:157 → 384
    PPP1R42; protein phosphatase 1 regulatory subunit 42
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8GRL7.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools