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KCS7 3-ketoacyl-CoA synthase 7 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 843456, updated on 18-Sep-2024

Summary

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Official Symbol
KCS7
Official Full Name
3-ketoacyl-CoA synthase 7
Primary source
TAIR:AT1G71160
Locus tag
AT1G71160
See related
Araport:AT1G71160
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
3-ketoacyl-CoA synthase 7; F23N20.15; F23N20_15
Summary
Encodes KCS7, a member of the 3-ketoacyl-CoA synthase family involved in the biosynthesis of VLCFA (very long chain fatty acids).
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Genomic context

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See KCS7 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
1
Sequence:
Chromosome: 1; NC_003070.9 (26828701..26830208, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene MATE efflux family protein Neighboring gene cyclin-D1-binding protein Neighboring gene 6-phosphogluconate dehydrogenase family protein Neighboring gene 6-phosphogluconate dehydrogenase family protein Neighboring gene senescence associated gene 18

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. CUT1, an Arabidopsis gene required for cuticular wax biosynthesis and pollen fertility, encodes a very-long-chain fatty acid condensing enzyme. Millar AA, et al. Plant Cell, 1999 May. PMID 10330468, Free PMC Article
  2. Tackling functional redundancy of Arabidopsis fatty acid elongase complexes. Batsale M, et al. Front Plant Sci, 2023. PMID 36798704, Free PMC Article
  3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables fatty acid elongase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cutin-based cuticle development IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within very long-chain fatty acid metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
3-ketoacyl-CoA synthase 7
NP_177272.1
  • 3-ketoacyl-CoA synthase 7 (KCS7); FUNCTIONS IN: transferase activity, transferring acyl groups other than amino-acyl groups, catalytic activity, acyltransferase activity; INVOLVED IN: very long-chain fatty acid metabolic process, cuticle development; LOCATED IN: endomembrane system, membrane; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage, E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: Thiolase-like (InterPro:IPR016039), Very-long-chain 3-ketoacyl-CoA synthase (InterPro:IPR012392), 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal (InterPro:IPR013747), FAE1/Type III polyketide synthase-like protein (InterPro:IPR013601), Thiolase-like, subgroup (InterPro:IPR016038); BEST Arabidopsis thaliana protein match is: 3-ketoacyl-CoA synthase 5 (TAIR:AT1G25450.1); Has 4929 Blast hits to 4911 proteins in 1102 species: Archae - 1; Bacteria - 1504; Metazoa - 0; Fungi - 34; Plants - 3243; Viruses - 0; Other Eukaryotes - 147 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    26828701..26830208 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_105785.2 → NP_177272.1  3-ketoacyl-CoA synthase 7 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_177272.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9C992
    UniProtKB/TrEMBL
    A0A178W4M1, A0A654EMZ9
    Conserved Domains (2) summary
    pfam08392
    Location:38 → 328
    FAE1_CUT1_RppA; FAE1/Type III polyketide synthase-like protein
    cl21486
    Location:348 → 416
    Ketoacyl-synt_C; Beta-ketoacyl synthase, C-terminal domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9C992.1

Gene LinkOut

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