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disease resistance protein (TIR-NBS-LRR class) [ Arabidopsis thaliana (thale cress) ]

Gene ID: 843291, updated on 18-Sep-2024

Summary

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Official Full Name
disease resistance protein (TIR-NBS-LRR class)
Primary source
TAIR:AT1G69550
Locus tag
AT1G69550
See related
Araport:AT1G69550
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F10D13.24; F10D13_24
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Genomic context

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Location:
chromosome: 1
Exon count:
4
Sequence:
Chromosome: 1; NC_003070.9 (26148021..26153600, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene expansin A1 Neighboring gene AGAMOUS-like 94 Neighboring gene ncRNA Neighboring gene miscRNA Neighboring gene miscRNA Neighboring gene myb domain protein 105

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

General gene information

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NM_105624.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ADP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
disease resistance protein (TIR-NBS-LRR class)
NP_564971.2
  • disease resistance protein (TIR-NBS-LRR class); FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: signal transduction, defense response, apoptosis, innate immune response; LOCATED IN: intrinsic to membrane, endomembrane system; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Disease resistance protein (InterPro:IPR000767), Toll-Interleukin receptor (InterPro:IPR000157); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) (TAIR:AT5G11250.1); Has 8455 Blast hits to 8197 proteins in 261 species: Archae - 0; Bacteria - 113; Metazoa - 3; Fungi - 4; Plants - 8303; Viruses - 0; Other Eukaryotes - 32 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    26148021..26153600 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_105624.5 → NP_564971.2  disease resistance protein (TIR-NBS-LRR class) [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_564971.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4I270, Q9C784
    Conserved Domains (7) summary
    cd09293
    Location:1053 → 1214
    AMN1; Antagonist of mitotic exit network protein 1
    cd00116
    Location:884 → 1132
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:934 → 957
    LRR_RI; leucine-rich repeat [structural motif]
    pfam00931
    Location:258 → 510
    NB-ARC; NB-ARC domain
    pfam01582
    Location:80 → 242
    TIR; TIR domain
    pfam07725
    Location:671 → 690
    LRR_3; Leucine Rich Repeat
    pfam13191
    Location:254 → 372
    AAA_16; AAA ATPase domain
Nucleotide Protein
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