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TADA tRNA arginine adenosine deaminase [ Arabidopsis thaliana (thale cress) ]

Gene ID: 843202, updated on 18-Sep-2024

Summary

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Official Symbol
TADA
Official Full Name
tRNA arginine adenosine deaminase
Primary source
TAIR:AT1G68720
Locus tag
AT1G68720
See related
Araport:AT1G68720
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS THALIANA TRNA ADENOSINE DEAMINASE A; ATTADA; F24J5.5; F24J5_5; tRNA arginine adenosine deaminase
Summary
Encodes the chloroplastic A-to-I tRNA editing enzyme.
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Genomic context

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See TADA in Genome Data Viewer
Location:
chromosome: 1
Exon count:
4
Sequence:
Chromosome: 1; NC_003070.9 (25804392..25809031)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ATPase E1-E2 type family protein / haloacid dehalogenase-like hydrolase family protein Neighboring gene uncharacterized protein Neighboring gene Zim17-type zinc finger protein Neighboring gene arabinogalactan protein 19

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Plastidial DIG5 Protein Affects Lateral Root Development by Regulating Flavonoid Biosynthesis and Auxin Transport in Arabidopsis. Liu W, et al. Int J Mol Sci, 2022 Sep 13. PMID 36142550, Free PMC Article
  2. Arabidopsis tRNA adenosine deaminase arginine edits the wobble nucleotide of chloroplast tRNAArg(ACG) and is essential for efficient chloroplast translation. Delannoy E, et al. Plant Cell, 2009 Jul. PMID 19602623, Free PMC Article
  3. Identification of the chloroplast adenosine-to-inosine tRNA editing enzyme. Karcher D, et al. RNA, 2009 Jul. PMID 19460869, Free PMC Article
  4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Disruption of TADA has profound effects on chloroplast translation efficiency, leading to reduced yields of chloroplast-encoded proteins and impaired photosynthetic function.
    Title: Arabidopsis tRNA adenosine deaminase arginine edits the wobble nucleotide of chloroplast tRNAArg(ACG) and is essential for efficient chloroplast translation.
Submit: New GeneRIF Correction

General gene information

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NM_105544.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables tRNA-specific adenosine deaminase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables tRNA-specific adenosine deaminase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables tRNA-specific adenosine-34 deaminase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in lateral root formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within tRNA wobble adenosine to inosine editing IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within tRNA wobble adenosine to inosine editing IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
tRNA arginine adenosine deaminase
NP_177039.1
  • tRNA arginine adenosine deaminase (TADA); FUNCTIONS IN: hydrolase activity, tRNA-specific adenosine deaminase activity, zinc ion binding; INVOLVED IN: tRNA wobble adenosine to inosine editing; LOCATED IN: chloroplast, plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: CMP/dCMP deaminase, zinc-binding (InterPro:IPR002125), Cytidine deaminase-like (InterPro:IPR016193); BEST Arabidopsis thaliana protein match is: Cytidine/deoxycytidylate deaminase family protein (TAIR:AT5G28050.1); Has 24755 Blast hits to 21172 proteins in 2784 species: Archae - 180; Bacteria - 9362; Metazoa - 5238; Fungi - 1033; Plants - 641; Viruses - 59; Other Eukaryotes - 8242 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    25804392..25809031
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_105544.3 → NP_177039.1  tRNA arginine adenosine deaminase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_177039.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8GY37, Q9S7I0
    UniProtKB/TrEMBL
    A0A178W371, A0A5S9WSS3
    Conserved Domains (1) summary
    COG0590
    Location:1110 → 1268
    TadA; tRNA(Arg) A34 adenosine deaminase TadA [Translation, ribosomal structure and biogenesis]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9S7I0.1

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